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Latest Lose Weight Fast auctions

Toni — Thu, 30 Dec 2010 03:33:48 +0000

lose weight fast eBay auctions you should keep an eye on:

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Q&A: How can i lose weight fast?

Toni — Fri, 24 Dec 2010 03:44:06 +0000

by robotgoboom

Question by star77: How can i lose weight fast?
ok so i am well over 100 pounds over weight , I am looking to lose this weight fast cause i need to lower my blood pressure and cholestorol and i would like suggestions on how to do it .
should i do a liquid diet ? has anyone tried that ?
im 26 female
thanks guys . and i know that its not healthy to lose fast but im already not healthy so..

Best answer:

Answer by Alison
diet and exercise.

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How to lose weight healthy, but also really fast?

Toni — Wed, 22 Dec 2010 03:36:28 +0000

by Ron Sombilon Gallery

Question by minda davis: How to lose weight healthy, but also really fast?
I’m not fat, but I am 20 lbs over weight, and I have bulky pars, not m-oobs, but still chub, and I want it to get lost fast, cuz is really annoying me.

I have a slower metabolism, and I have been fat all of my life. I am thirteen, and I want too lose it.

How can a buysy person that dosn’t have alot of time for anything, lose weight fast?

Best answer:

Answer by Seal
Eat correctly…Stay away from SUGAR!!!! Also you should exercise EVERY day …Try just running around the block everyday….Simple exercise can really make a difference at your age.. Just drinking water for a whole month and not drinking soft drinks, entergy drinks, or drinks like Powerade can make you lose about 10 pounds in a month…

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Lose Weight Fast Diets — Does that exist?

Toni — Sat, 18 Dec 2010 03:43:52 +0000

by striatic

Lose weight fast diets are all over television channels, internet sites, news stands, radio airwaves, and anywhere else they can possible be seen or heard advertised. These diets are big business in America. Why are these diets such a huge influence over our lives? Well, statistics are showing that almost 60% of Americans are now in the over weight to obese spectrum. People are desperate to lose the extra weight and these lose weight fast diets promise quick weight loss.

Some of these diets promote unsafe eating habits, which do nothing but set the dieter up for failure. But some of the popular lose weight fast diets are based on sound diet advice and can actually be a healthy and fast way to lose weight. As long as the main principles behind the diet are healthy eating habits and they promote exercise along with better eating habits, the diet will work for most. Remember that cutting out whole food groups or cutting calories to dangerous levels will only force your body into starvation mode, causing more harm than good to your metabolism and health in general.

The types of diets that you should be looking for when considering lose weight fast diets, are diets that promote healthy eating. If the diet does not sound safe, it probably isn’t. You probably already know that yo-yo dieting can ruin your health and actually stall weight loss. Make sure that the diet you are looking to try includes healthy food choices, adequate calories per day, and plenty of fruits and vegetables to make sure your body is getting all of the vitamins, minerals and fiber that it needs to function properly.

Diets that promote at least 1,000 calories or more per day for women and 1,600 per day for men should be avoided at all costs. These diets (dubbed fad diets) can cause more harm to your body than good and will stall your metabolism causing your weight loss efforts to fail.

It is important to remember also that exercise is a very important part of any weight loss program. Exercise is just as important as calorie restriction when you are trying to lose weight. This is why it is imperative when you are looking at lose weight fast diets to try, that the diet incorporates at least 20 minutes of exercise in addition to a healthy meal plan. Exercising does not have to consume your entire day, every day. There are simple ways to fit in your daily exercise and a diet that promotes this fact is sure to be a sound diet that is worth trying.

Whatever diet you decide to choose, remember that your health is always at stake. A diet that could potentially cause your health to fail in the future is not a diet worth trying. However, a diet program that promotes a healthy lifestyle and long term diet changes can literally be a life saver. No matter what diet plan you decide to try, remember that only you can change your life.

Stephen Choy, editor of Fast Weight Loss. For more information on how to get healthy and lose weight quickly and easily, click quickly lose weight now!

Article from articlesbase.com

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SUPERFOOD MAX: LOSE WEIGHT FAST DIET PILLS ANTI-AGING

Toni — Fri, 10 Dec 2010 03:41:35 +0000

Lose Weight Fast on eBay:

BIKINI BLAST FITNESS: LOSE WEIGHT FAST – NEW DVD BOXSET

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OmneSlim – Quickly Lose Weight Loss Fast Burn Appetite Suppressant #1 PILLS BEST

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How To Lose Weight Fast and Easy

Toni — Wed, 08 Dec 2010 03:37:58 +0000

This tells how I lost over 100 pounds, hope you can make some use of it

Tags: Health Medical Pharma, Human Interest, lose, lose weight fast

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HCG Diet Direct Supports New Study Results Indicating a Fast Way to Lose Weight is Most Efficient

Toni — Sat, 04 Dec 2010 03:44:25 +0000

HCG Diet Direct Supports New Study Results Indicating a Fast Way to Lose Weight is Most Efficient

HCG Diet Direct

Phoenix, AZ (Vocus) August 2, 2010

HCG Diet Direct cites a new study that indicates that a fast way to lose weight is the most efficient method for long term weight loss. Dr. Jeroen Barte, a researcher at the National Institute for Public Health and the Environment in the Netherlands along with his colleagues presented the findings of their study at the International Congress on Obesity in Stockholm, Sweden on Monday, July 12, 2010.

Barte and colleagues’ findings indicated that regardless of how much weight an individual loses they typically gain back half of the “weight lost” in the following year. That means that dieters who lost a drastic amount of weight initially ended up with the most weight loss in the long term. The researchers concluded that experts should encourage dieters to lose 10% or more of their weight in order to achieve the maximum, long term weight loss results.

Dr. J. Ronald Willis of HCG Diet Direct said, “There has been a stigma placed on any ‘fast way to lose weight’ for years. Recent studies are indicating that this is a mistake. Not only is it a mistake, but it’s a drastic mistake. Every tool should be used in order to overcome the obesity epidemic. And for most…a fast way to lose weight is the most effective method.”

Homeopathic HCG weight loss formula is a fast weight loss diet that can be used to achieve drastic weight loss without invasive procedures. The HCG drops are taken three times daily and paired with a careful eating plan.

The results of the standard 26-30 day program can provide an average of 1 to 2 pounds of weight loss per day.

To get further information on HCG Diet Direct or the HCG Diet contact:

Contact: Dr. J. Ronald Willis

Company: HCG Diet Direct

http://www.hcgdietdirect.com

Phone: 602-916-0002

###

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How to Lose Weight: Quick Weight-Loss Workout to Lose 15 Pounds Fast

Toni — Fri, 02 Jul 2010 03:56:55 +0000

Losing 15 pounds in a short amount of time requires a reduced-calorie diet and regular cardiovascular exercise. Shed 15 pounds in no time withhelp from a certified personal trainer in this free video on losing weight. Expert: Tanya Batts Contact: www.goldsgym.com Bio: Tanya Batts has been a certified personal fitness trainer for more than 11 years. Filmmaker: Reel Media LLC

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3 DAY DIET PLAN REALLY WORKS: I HAVE LOST 65 POUNDS IN 12 WEEKS: FAST WEIGHT LOSS DIET:

Toni — Sat, 17 Apr 2010 06:15:45 +0000

www.getfatfreebody.com the 3 day diet plan 3 day detox 3 day cleanse three day diet, diets, plans, FAST WEIGHT LOSS DIET program for WOMEN FAST weight loss before and after fast weight loss pills

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The original post is located: 3 DAY DIET PLAN REALLY WORKS: I HAVE LOST 65 POUNDS IN 12 WEEKS: FAST WEIGHT LOSS DIET:

Fast Weight Loss workout exercises to lose 5 lbs. a week

Toni — Sun, 04 Apr 2010 04:56:43 +0000

From www.nowloss.com This fast weight loss workout has 5 different exercises you do that’ll help you lose up to 5 pounds a week and once you get to a point where you are not satisfied with how fast you’re losing weight on this fast weight loss workout plan then… You can do my other youtube video called “Quick weight loss workout to help YOU Lose 15 pounds fast” to shock your body so you’ll break out of any weight loss plateau you’re in so you can lose weight fast again and… Remember – The KEY THING is that you at least try to finish this fast weight loss workout and work your way up to taking less rest time between exercises – for example… Let’s say that during this fast weight loss workout — you have a hard time doing all 15 power cleans in a row — just do about 2 or 3 at a time — catch your breath — and then finish. Eventually — you’ll be able to finish most of the workout by only stopping in between exercises for your mandatory rest periods and… You can go here to print out this fast weight loss workout routine for losing 5 pounds a week www.nowloss.com and… Guys: you can use heavier weights and do only 8-to-12 reps for each exercise with this fast weight loss workout to burn fat and build muscle at the same time and… Ladies: you can use lighter weights and do 15-to-25 reps to lose weight fast while toning and firming up your body and… How fast you lose 5 pounds a week all depends on… *How much you weigh — the more overweight you are –the more …

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Clinical Signs of Temporomandibular Disorders and Various Pain Conditions Among Children 6 to 8 Years of Age: The PANIC Study.

Pain Physician — Sun, 05 Feb 2012 17:36:02 +0100

Conclusion: Clinical signs of TMD and pain symptoms are common in children. The relationship of back pain, neck-shoulder muscle palpation tenderness, and headache with clinical signs of TMD suggests that more attention should be paid to stomatognathic function in children with such pain problems. J Orofac Pain 2012;26:17-25. PMID: 22292136 [PubMed - in process] (Source: Pain Physician)

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How to cope with backache

Telegraph Health — Sun, 05 Feb 2012 07:00:57 +0100

All you need to know about treating and preventing back pain, by the chiropractor Dominic Cheetham (Source: Telegraph Health)

Low back pain in 17 year olds has substantial impact and represents an important public health disorder: a cross-sectional study

BMC Public Health - Latest articles — Sun, 05 Feb 2012 05:00:00 +0100

Conclusion: LBP, and particularly chronic LBP, has a significant negative impact at 17 years. It is commonly associated with care seeking, medication use, school absenteeism, and reduced HRQOL. These findings support that adolescent LBP is an important public health issue that requires attention. (Source: BMC Public Health - Latest articles)

[Seminar] Non-specific low back pain

LANCET — Sat, 04 Feb 2012 05:00:00 +0100

Non-specific low back pain has become a major public health problem worldwide. The lifetime prevalence of low back pain is reported to be as high as 84%, and the prevalence of chronic low back pain is about 23%, with 11–12% of the population being disabled by low back pain. Mechanical factors, such as lifting and carrying, probably do not have a major pathogenic role, but genetic constitution is important. History taking and clinical examination are included in most diagnostic guidelines, but the use of clinical imaging for diagnosis should be restricted. (Source: LANCET)

What Do I Do With My Paper Chart? — The Middle of the Road Makes the Most Sense

ICMCC: The International Council on Medical and Care Compunetics — Fri, 03 Feb 2012 09:00:43 +0100

Source: Seth Flam, Becker's Orthopedic, Spine & Pain Management Content: “Many healthcare providers who are transitioning from paper charts to electronic health records need help understanding how to work with the paper charts they built over their many years in practice. There are three general approaches.” Article Seth Flam, Becker’s Orthopedic, Spine & Pain Management, 2 February [...] (Source: ICMCC: The International Council on Medical and Care Compunetics)

Series of 8 cases of Irukandji syndrome? or bait-and-switch

The Poison Review — Fri, 03 Feb 2012 07:23:04 +0100

1.5 out of 5 stars Irukandji Sydrome [sic] in the Torres Strait: A Series of 8 Cases. McIver LJ et al. Wilderness Environ Med 2011;22:338-342. Abstract The problems with this paper merely begin with the dropped “n” in the second word of the title. Then we get to the first sentence of the abstract, where despite the title’s promise of a case series of Irukandji syndrome (or sydrome, or whatever) we find a classic medical literature bait-and-switch: Objective–To review the presentations of a series of patients with suspected Irukandji syndrome in the Torres Strait, where the syndrome has hitherto been unknown or undocumented, in order to identify at-risk groups and improve the management of this condition in the region. So we’re dealing not with cases of Irukan...

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Kneeling Arm and Leg Reach

About.com Eating Disorders — Fri, 03 Feb 2012 05:00:00 +0100

This Pilate move, the opposite arm and leg reach exercise, can help balance and relive back pain by building core strength and stability. This is one of the Pilates exercises recommended for back pain. (Source: About.com Eating Disorders)

A rare gastrointestinal presentation of a common malignancy

Gut — Fri, 03 Feb 2012 05:00:00 +0100

Clinical presentation A 61-year-old man presented with a 4-week history of rectal bleeding, constipation, bloating, abdominal distension and low back pain. His bowels had not opened for 4 days prior to admission. Physical examination revealed a distended, tympanic abdomen. Routine laboratory tests confirmed renal failure (urea 13 mmol/l, creatinine 200 μmol/l), hypercalcaemia (3.7 mmol/l), albumin 32 g/l and C-reactive protein (CRP) 25 mg/l. Parathormone was suppressed (7 pg/l (15–65)). Abdominal x-ray suggested an ileus. CT abdomen revealed mural thickening of the left hemi-colon along with collapse of the third lumbar vertebra. An isotope bone scan was unremarkable, while MRI of the spine confirmed the presence of multiple lytic lesions. Immuno...

Expansion of Research in Chiropractic Care is Ushering in New Era of Evidence-Based Therapies, Says American Specialty Health

Medical News (via PRIMEZONE) — Thu, 02 Feb 2012 11:00:00 +0100

SAN DIEGO, Feb. 2, 2012 (GLOBE NEWSWIRE) -- On the heels of new research showing that spinal manipulation and exercise are effective in relieving neck pain, American Specialty Health (ASH), one of the nation's leading providers of chiropractic health care benefits, said today that the expansion of research in chiropractic care is leading to big changes in the way chiropractic medicine is practiced and perceived in the United States. (Source: Medical News (via PRIMEZONE))

Long-Term Financial Disadvantage Faced By Those Who Retire Early Due To Back Problems

Health News from Medical News Today — Thu, 02 Feb 2012 09:00:00 +0100

Back problems are a highly prevalent health issue, and people with the condition have a significantly greater chance of retiring early from the workforce, much more so than for any other health condition. A group of Australian researchers reports that not only does early retirement limit the immediate income available to these individuals, but it also reduces their long-term financial capacity, by reducing their ability to accumulate wealth to a significant degree. Their study is published in the January issue of Pain®... (Source: Health News from Medical News Today)

Life‐threatening cervical spine collapse as a result of postradiation osteonecrosis—case report and review of the literature

Head and Neck — Thu, 02 Feb 2012 05:00:00 +0100

ConclusionDelayed diagnosis of cervical ORN can result in marked disability and pain due to spinal cord compression, as well as serious deformity and instability requiring surgical intervention, and even death. It is important for otolaryngologists who treat head and neck malignancies to be aware of this potential complication so that patients may be diagnosed as early as possible and treated with conservative measures. © 2012 Wiley Periodicals, Inc. Head Neck, 2012 (Source: Head and Neck)

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Up-regulation of platelet-activating factor synthases and its receptor in spinal cord contribute to development of neuropathic pain following peripheral nerve injury

Molecular Pain — Thu, 02 Feb 2012 05:00:00 +0100

Conclusions: Our data show the histological localization of PAF synthases and its receptor in the spinal cord following peripheral nerve injury, and suggest that PAF/PAFr signaling in the spinal cord acts in an autocrine or paracrine manner among the activated microglia and neurons, thus contributing to development of neuropathic pain. (Source: Molecular Pain)

Intracutaneous or subcutaneous sterile water injection compared with blinded controls for pain management in labour

NeLM - Drug Specific Reviews — Thu, 02 Feb 2012 05:00:00 +0100

Source: Cochrane Library Area: Evidence > Drug Specific Reviews Background Intracutaneous or subcutaneous injection of sterile water is rapidly gaining popularity as a method of pain relief in labour and it is therefore essential that it is properly evaluated. Adequate analgesia in labour is important to women worldwide. Sterile water injection is inexpensive, requires basic equipment, and appears to have few side effects. It is purported to work for labour pain. Objectives To determine the efficacy of sterile water injections for relief of pain (both typical contraction pain and intractable back pain) during labour compared to placebo (isotonic saline injections) or non-pharmacological interventions, and to identify any relevant effects on mode and timing of delivery, or ...

Plasma Cell Myeloma

Diagnostic Imaging — Wed, 01 Feb 2012 12:00:00 +0100

Clinical History: A 31-year-old man with back pain. X-Ray Chest: Lower thoracic paravertebral soft issue with trabeculated T9. Lungs are clear. Heart size within normal limit. No other obvious bony abnormality. (Source: Diagnostic Imaging)

IRS2 signalling is required for the development of a subset of sensory spinal neurons

European Journal of Neuroscience — Wed, 01 Feb 2012 05:00:00 +0100

AbstractInsulin and insulin‐like growth factor‐I play important roles in the development and maintenance of neurons and glial cells of the nervous system. Both factors activate tyrosine kinase receptors, which signal through adapter proteins of the insulin receptor substrate (IRS) family. Although insulin and insulin‐like growth factor‐I receptors are expressed in dorsal root ganglia (DRG), the function of IRS‐mediated signalling in these structures has not been studied. Here we address the role of IRS2‐mediated signalling in murine DRG. Studies in cultured DRG neurons from different embryonic stages indicated that a subset of nerve growth factor‐responsive neurons is also dependent on insulin for survival at very early time points. Consistent with this, increased apoptosis d...

Ergonomics: Back to the Future

Ophthalmology — Wed, 01 Feb 2012 05:00:00 +0100

The frequency of musculoskeletal disorders (MSD) has been reported in the ophthalmic literature over the last decade. Based upon different criteria, survey instruments, and populations studied, the prevalence of MSD symptoms in ophthalmologists varies. Kitzmann et al report the first study that compares MSD symptoms in ophthalmologists to family medicine doctors at 2 institutions using the same survey instrument. Ophthalmologists reported a statistically significant increased prevalence of neck, hand/wrist, and lower back pain in comparison to their family medicine doctor colleagues. Although the number of ophthalmologists surveyed was relatively low, and findings in practice settings as opposed to these 2 academic institutions may differ, the rates of symptoms among ophthalmologists were ...

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Restoration of lordosis and disk height after single‐level transforaminal lumbar interbody fusion

Orthopaedic Surgery — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: Intervertebral height and lumbar lordosis reconstruction are important for achieving good surgical results; guidance regarding the likely changes in lumbar lordosis and disk height after TLIF is provided by our findings. (Source: Orthopaedic Surgery)

Multifidus Atrophy Is Localized and Bilateral in Active Persons With Chronic Unilateral Low Back Pain

Archives of Physical Medicine and Rehabilitation — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: The results of this study indicate that despite a low level of disability and an activity level similar to that of matched control subjects, considerable localized, bilateral multifidus atrophy is present. Such impaired size of the multifidus will likely reduce its capacity to control intersegmental motion, thus increasing the susceptibility to further injury. Unlike acute unilateral low back pain (LBP), muscle size is reduced bilaterally in persons with chronic unilateral LBP. (Source: Archives of Physical Medicine and Rehabilitation)

Behavioral Factors Related to Fatigue Among Persons With Spinal Cord Injury

Archives of Physical Medicine and Rehabilitation — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: We identified several behavioral predictors of disabling fatigue, including cardiovascular risk factors, prescription medication use, and alcohol use. These factors are important because they are able to be modified and could be potential factors for prevention or intervention. (Source: Archives of Physical Medicine and Rehabilitation)

Prevalence of Anatomic Impediments to Interlaminar Lumbar Epidural Steroid Injection

Archives of Physical Medicine and Rehabilitation — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: Anatomic impediments to interlaminar LESI were common in this community-based population, particularly at the L5-S1 spinal level. Because of the high overall prevalence of anatomic impediments, and differences in prevalence by spinal level, knowledge of the distribution and frequency of these impediments may aid in aspects of decision-making for the interventional spine physician. (Source: Archives of Physical Medicine and Rehabilitation)

Short-Term Effect of Superficial Heat Treatment on Paraspinal Muscle Activity, Stature Recovery, and Psychological Factors in Patients With Chronic Low Back Pain

Archives of Physical Medicine and Rehabilitation — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: Use of the heat wrap was associated with a decrease in muscle activity and a short-term improvement in certain aspects of well-being for the CLBP patients. The results confirm the link between the biomechanical and psychological outcome measures. (Source: Archives of Physical Medicine and Rehabilitation)

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Prevalence of anatomic impediments to interlaminar lumbar epidural steroid injection.

Pain Physician — Wed, 01 Feb 2012 05:00:00 +0100

CONCLUSIONS: Anatomic impediments to interlaminar LESI were common in this community-based population, particularly at the L5-S1 spinal level. Because of the high overall prevalence of anatomic impediments, and differences in prevalence by spinal level, knowledge of the distribution and frequency of these impediments may aid in aspects of decision-making for the interventional spine physician. PMID: 22289247 [PubMed - in process] (Source: Pain Physician)

Early Retirement Due to Bad Back Problems

Disabled World — Tue, 31 Jan 2012 21:32:43 +0100

People who retire early due to back problems face long-term financial disadvantage. (Source: Disabled World)

Early Retirement Due to Back Pain

Disabled World — Tue, 31 Jan 2012 21:32:00 +0100

People who retire early due to back problems face long-term financial disadvantage. (Source: Disabled World)

Natural language processing in EMRs can improve disease tracking

ICMCC: The International Council on Medical and Care Compunetics — Tue, 31 Jan 2012 11:09:31 +0100

Source: Jaan Sidorov, KevinMD Content: “Years ago, if you were elderly, had diabetes, high blood pressure, low back pain, needed a yearly flu shot and came to see this electronic health record-enabled physician (now with the nom de plume “Disease Management Care Blog”), you would have had your diabetes, high blood pressure and low back [...] (Source: ICMCC: The International Council on Medical and Care Compunetics)

People who retire early due to back problems face long-term financial disadvantage

EurekAlert! - Social and Behavioral Science — Tue, 31 Jan 2012 05:00:00 +0100

(Elsevier Health Sciences) Back problems are a highly prevalent health issue, and people with the condition have a significantly greater chance of retiring early from the workforce, much more so than for any other health condition. A group of Australian researchers reports that not only does early retirement limit the immediate income available to these individuals, but it also reduces their long-term financial capacity, by reducing their ability to accumulate wealth to a significant degree. Their study is published in the January issue of Pain. (Source: EurekAlert! - Social and Behavioral Science)

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Effects of an exercise programme on musculoskeletal and neuropathic pain after spinal cord injury—results from a seated double-poling ergometer study

Spinal Cord — Tue, 31 Jan 2012 05:00:00 +0100

Effects of an exercise programme on musculoskeletal and neuropathic pain after spinal cord injury—results from a seated double-poling ergometer study Spinal Cord advance online publication, January 31, 2012. doi:10.1038/sc.2011.160 Authors: C Norrbrink, T Lindberg, K Wahman & A Bjerkefors (Source: Spinal Cord)

BARHL2 transcription factor regulates the ipsilateral/contralateral subtype divergence in postmitotic dI1 neurons of the developing spinal cord [Developmental Biology]

Proceedings of the National Academy of Sciences — Tue, 31 Jan 2012 05:00:00 +0100

In the dorsal spinal cord, distinct interneuron classes relay specific somatosensory information, such as touch, heat, and pain, from the periphery to higher brain centers via ipsilateral and contralateral axonal pathways. The transcriptional mechanisms by which dorsal interneurons choose between ipsilateral and contralateral projection fates are unknown. Here, we show that a single transcription factor (TF), BARHL2, regulates this choice in proprioceptive dI1 interneurons by selectively suppressing cardinal dI1contra features in dI1ipsi neurons, despite expression by both subtypes. Strikingly, dI1ipsi neurons in Barhl2-null mice exhibit a dI1contra cell settling pattern in the medial deep dorsal horn, and, most importantly, they project axons contralaterally. These aberrations are precede...

Fast Synaptic Inhibition in Spinal Sensory Processing and Pain Control

Physiological Reviews — Tue, 31 Jan 2012 05:00:00 +0100

The two amino acids GABA and glycine mediate fast inhibitory neurotransmission in different CNS areas and serve pivotal roles in the spinal sensory processing. Under healthy conditions, they limit the excitability of spinal terminals of primary sensory nerve fibers and of intrinsic dorsal horn neurons through pre- and postsynaptic mechanisms, and thereby facilitate the spatial and temporal discrimination of sensory stimuli. Removal of fast inhibition not only reduces the fidelity of normal sensory processing but also provokes symptoms very much reminiscent of pathological and chronic pain syndromes. This review summarizes our knowledge of the molecular bases of spinal inhibitory neurotransmission and its organization in dorsal horn sensory circuits. Particular emphasis is placed on the rol...

Those Extra Pounds Could Harm Your Back

MedicineNet Chronic Pain General — Mon, 30 Jan 2012 07:00:00 +0100

Title: Those Extra Pounds Could Harm Your BackCategory: Health NewsCreated: 1/30/2012 10:05:00 AMLast Editorial Review: 1/30/2012 (Source: MedicineNet Chronic Pain General)

Endoscopic management of a lower clival chondroid chordoma: case report.

Turkish Neurosurgery — Mon, 30 Jan 2012 05:00:02 +0100

We report herein a case of lower clival chondroid chordoma, focusing on the surgical procedure of endoscopic endonasal surgery. A 36-yearold woman presented with progressive headache, right shoulder pain, and right hypoglossal nerve palsy. Computed tomography (CT) and magnetic resonance (MR) imaging revealed an extradural tumor located in the lower clivus, including the anterior aspect of the foramen magnum, deeply compressing the medulla and upper cervical spinal cord. Endoscopic endonasal surgery was performed via two nostrils. Since the basiocciput was destroyed by the tumor, removal of the tumor allowed identification of the middle clivus superiorly, the anterior arch of the atlas inferiorly, and anteromedial parts of occipital condyles bilaterally without drilling ...

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The Effect of KinesioTape Application on Functional Performance in Surgeons Who have Musculo-Skeletal Pain after Performing Surgery.

Turkish Neurosurgery — Mon, 30 Jan 2012 05:00:02 +0100

CONCLUSION: Findings demonstrated that Kinesio taping would be an effective method for reducing neck and low back pain and improving functional performance. PMID: 22274976 [PubMed - in process] (Source: Turkish Neurosurgery)

Excitability of Abeta sensory neurons is altered in an animal model of peripheral neuropathy

BMC Neuroscience - Latest articles — Mon, 30 Jan 2012 05:00:00 +0100

Conclusions: The present study has demonstrated changes in functionally classified Abeta low threshold and high threshold DRG neurons in a nerve intact animal model of peripheral neuropathy that demonstrates nociceptive responses to normally innocuous cutaneous stimuli, much the same as is observed in humans with neuropathic pain. We demonstrate further that the peripheral receptive fields of these neurons are more excitable, as are the somata. However, the dorsal roots exhibit a decrease in excitability. Thus, if these neurons participate in neuropathic pain this differential change in excitability may have implications in the peripheral drive that induces central sensitization, at least in animal models of peripheral neuropathic pain, and Abeta sensory neurons may thus contribute to allo...

Literally – the much misused word of the moment

Guardian Unlimited Science — Sun, 29 Jan 2012 20:30:00 +0100

It's like literally so misoverused. But whereas Jamie Redknapp gets the word nonsensically wrong, writers such as James Joyce knew exactly what they were doing with itI was sitting in a cafe – one of those generic pain au raisin and latte joints, with an earnest singer-songwriter soundtrack to boot – when a kid to my left piped up: "My school gym is like literally 500 years old." His friends nodded with conviction. They understood. They felt the appalling deprivation of it all. A 500-year-old cross-trainer just isn't any good to anybody. But I wasn't going to underestimate my table-neighbour just yet. I couldn't give up on him like that. After all, I appreciated the subtle contradiction of that "like", poised on the edge of potential simile, and that bold, indicative "literal...

Inhaled Oxygen for Cluster Headache: Efficacy, Mechanism of Action, Utilization, and Economics

Current Pain and Headache Reports — Sat, 28 Jan 2012 16:52:05 +0100

This article examines various issues regarding inhaled oxygen and cluster headache, including efficacy, proposed mechanism of action, utilization, and the economics of oxygen usage for cluster headache patients. Much of the data analyzed comes from the recently published United States Cluster Headache Survey. This is the largest study of cluster headache patients ever published and is the first study to focus on inhaled oxygen and cluster headache in a large, non-clinic-based population. Content Type Journal ArticleCategory Trigeminal Autonomic Cephalalgias (M Matharu, Section Editor)Pages 1-5DOI 10.1007/s11916-012-0246-2Authors Todd D. Rozen, Geisinger Specialty Clinic, MC 37-31, 1000 East Mountain Drive, Wilkes-Barre, PA 18711, USA Journal Current Pain and Headache Repor...

2. The blink reflex: Long known, but still fascinating

Clinical Neurophysiology — Sat, 28 Jan 2012 16:42:16 +0100

The blink reflex is routinely used in clinical neurophysiology to characterize the functional integrity of the trigemino-facial reflex pathway covering supraorbital nerve, pons, medulla oblongata, and facial nerve. Recent findings of unconditioned blink reflex alterations, as well as changes in blink reflex modulation by subthreshold prepulse stimuli or suprathreshold double pulse stimulation, in patients with spinal cord injury or chronic pain syndromes, e.g. fibromyalgia, suggest plastic changes at the brainstem level in these conditions. The blink reflex and its modulation also serve to document acute pharmacological effects, e.g. following intrathecal bolus application of the GABA-ergic drug baclofen, thus concurring with an antispastic action of baclofen at the brainstem level. Finall...

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10 Best Practices for Implementing Telemedicine in Hospitals

ICMCC: The International Council on Medical and Care Compunetics — Sat, 28 Jan 2012 11:09:46 +0100

Source: Sabrina Rodak, Becker's Orthopedic, Spine & Pain Management Content: “Telemedicine and telehealth have the potential to increase access to care, improve quality of care and decrease costs. For instance, the American Telemedicine Association proposed legislation that would expand telemedicine and save an estimated $186 million over the next 10 years. In addition, the U.S. [...] (Source: ICMCC: The International Council on Medical and Care Compunetics)

Relationship of orthopedic examination, goniometric measurements, and radiographic signs of degenerative joint disease in cats

BMC Veterinary Research - Latest articles — Fri, 27 Jan 2012 05:00:00 +0100

Conclusions: Radiographic DJD cannot be diagnosed with certainty using palpation or goniometry. However, negative findings tend to predict radiographically normal joints. Palpation and goniometry may be used as a tool to help to screen cats, mostly to rule out DJD. (Source: BMC Veterinary Research - Latest articles)

Prevention of Development of Postoperative Dysesthesia in Transforaminal Percutaneous Endoscopic Lumbar Discectomy for Intracanalicular Lumbar Disc Herniation: Floating Retraction Technique

min - Minimally Invasive Neurosurgery — Fri, 27 Jan 2012 05:00:00 +0100

Minim Invasive Neurosurg 2011; 54: 214-218DOI: 10.1055/s-0031-1287774Transforaminal percutaneous endoscopic lumbar discectomy (PELD) has become a routine surgical procedure because it is minimally invasive. Perioperative complications such as dural injury, infection, nerve root irritation and recurrence can occur not only with PELD, but also with conventional open microsurgery. In contrast, post-operative dysesthesia (POD) due to existing dorsal root ganglion (DRG) injury is a unique complication of PELD. When POD occurs, even if the traversing root has been successfully decompressed, it hinders swift recovery and delays the return to daily routines. Thus, prevention of POD is the key to successful and widespread use of PELD.From January 2006 to December 2008, 154 patients underwent percut...

Propagation of Spinal Nociceptive Activity in the Spatial and Temporal Domains

The Neuroscientist — Fri, 27 Jan 2012 05:00:00 +0100

Nociceptive stimuli are transmitted through thinly myelinated or unmyelinated primary afferent fibers called nociceptors, which terminate mainly in the superficial dorsal horn of the spinal cord. While most nociceptive fibers terminate in the spinal segment of the entrance, (collateral) fibers may ascend and descend several segments upon their entry into the spinal cord, which is reflected in the receptive fields of central nociceptive neurons. In chronic pain states like inflammatory or neuropathic pain, the area of nociceptive activity may expand even further in rostrocaudal and mediolateral directions. Also, within minutes (inflammatory pain) or days (neuropathic pain), an increased sensitivity of peripheral and central nociceptive neurons will develop, which is referred to as sensitiza...

Pseudoaneurysm of Lumbar Artery following a Vertebral Biopsy: A Case Report

Advances in Pharmacological Sciences — Thu, 26 Jan 2012 18:56:20 +0100

A 74-year-old man developed a severe low back pain and a fever. In the initial examinations, a collapse of the L5 anterosuperior vertebral body and narrowing of the L4/5 disc space were identified on radiographs, and the laboratory data showed inflammatory results. A computed tomography (CT) and a magnetic resonance imaging showed collapse of L5. A needle biopsy was performed to make a diagnosis; however, an abdominal pain and a hypotension appeared after the biopsy. An abdominal CT showed a hematoma in the retroperitoneal space, and an angiography revealed a left fourth lumbar artery pseudoaneurysm. The pseudoaneurysm was treated with transcatheter placement of microcoils. Although haemorrhagic complications following needle biopsy are very rare, patients with large amounts of vertebral d...

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Exercise may boost mood for some chronically ill

Reuters: Health — Thu, 26 Jan 2012 18:37:54 +0100

NEW YORK (Reuters Health) - Working out regularly may brighten the mood of people with chronic health problems like cancer, heart disease and back pain, according to the first sweeping look at previous research. (Source: Reuters: Health)

A Double‐blind, Randomized, Prospective Study of Epidural Steroid Injection vs. The mild® Procedure in Patients with Symptomatic Lumbar Spinal Stenosis

Pain Practice — Thu, 26 Jan 2012 12:10:25 +0100

Conclusions: This study demonstrated that in LSS patients suffering with neurogenic claudication, mild provides statistically significantly better pain reduction and improved functional mobility vs. treatment with ESI. (Source: Pain Practice)

Intracutaneous or subcutaneous sterile water injection compared with blinded controls for pain management in labour.

Cochrane Database of Systematic Reviews — Thu, 26 Jan 2012 08:18:08 +0100

CONCLUSIONS: The outcomes reported severely limit conclusions for clinical practice. We found little robust evidence that sterile water is effective for low back or any other labour pain. Neither did we find any difference in delivery or other maternal or fetal outcomes. Further large, methodologically rigorous studies are required to determine the efficacy of sterile water to relieve pain in labour. PMID: 22258999 [PubMed - in process] (Source: Cochrane Database of Systematic Reviews)

Spinal tuberculosis occurring after a closed bursting fracture of the vertebrae

European Spine Journal — Thu, 26 Jan 2012 06:57:06 +0100

Conclusion In developing countries, where TB is still widely prevalent, there must be a heightened awareness of the risk of ST at recently fractured vertebrae, as demonstrated in this case. Content Type Journal ArticleCategory Case ReportPages 1-6DOI 10.1007/s00586-012-2149-7Authors Bo Huang, Department of Orthopedics, Xinqiao Hospital, The Third Military Medical University, Chongqing, 400037 People’s Republic of ChinaChang-Qing Li, Department of Orthopedics, Xinqiao Hospital, The Third Military Medical University, Chongqing, 400037 People’s Republic of ChinaYing Zhuang, Department of Orthopedics, Xinqiao Hospital, The Third Military Medical University, Chongqing, 400037 People’s Republic of ChinaJian-Ping Xu, Department of Pathology, Xinqiao Hospital, The Thir...

Well Blog: The Kettlebell Workout for Back and Neck Pain

NYT Health — Thu, 26 Jan 2012 05:01:36 +0100

Kettle-shaped iron weights, which have been used for centuries to train Russian soldiers and athletes, appear to be a promising therapy for back, neck and shoulder pain, new research shows. (Source: NYT Health)

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Can Supervised Group Exercises Including Ergonomic Advice Reduce the Prevalence and Severity of Low Back Pain and Pelvic Girdle Pain in Pregnancy? A Randomized Controlled Trial.

Physical Therapy — Thu, 26 Jan 2012 05:00:00 +0100

CONCLUSIONS:/st>Supervised group exercise did not reduce the prevalence of LBP or PGP in pregnancy. PMID: 22282770 [PubMed - as supplied by publisher] (Source: Physical Therapy)

Exercise may boost mood for some chronically ill

Reuters: Health — Wed, 25 Jan 2012 22:31:17 +0100

Exercise May Boost Mood for Some Chronically Ill

MedlinePlus Health News — Wed, 25 Jan 2012 22:30:54 +0100

Working out regularly may brighten the mood of people with chronic health problems like cancer, heart disease and back pain, according to the first sweeping look at previous research.Source: Reuters Health Related MedlinePlus Pages: Coping with Chronic Illness, Exercise and Physical Fitness (Source: MedlinePlus Health News)

The effect of abdominal and pelvic floor muscle activation on urine flow in women

International Urogynecology Journal — Wed, 25 Jan 2012 18:12:16 +0100

Conclusions These data provide evidence that specific abdominal muscle manoeuvres influence urethral closure in continent women, and this is probably mediated by concurrent activation of PFM during the abdominal task. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00192-011-1654-2Authors Ruth R. Sapsford, NHMRC Centre of Clinical Research Excellence in Spinal Pain, Injury and Health, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Queensland, Australia 4072Paul W. Hodges, NHMRC Centre of Clinical Research Excellence in Spinal Pain, Injury and Health, School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Queensland, Australia 4072 Journal International Urogynecolog...

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Predictive factors of cervical spondylotic myelopathy in patients with lumbar spinal stenosis

Archives of Orthopaedic and Trauma Surgery — Wed, 25 Jan 2012 18:07:45 +0100

Conclusion Torg-Pavlov ratio was the most important predictive factor of CSM in patients with LSS. Content Type Journal ArticleCategory Orthopaedic SurgeryPages 1-5DOI 10.1007/s00402-012-1465-zAuthors Hideki Iizuka, Department of Orthopaedic and Spinal Surgery, Saitama Mediclal University, Morohongo 38, Moroyama, Iruma, Saitama 350-0495, JapanKeisuke Takahashi, Department of Orthopaedic and Spinal Surgery, Saitama Mediclal University, Morohongo 38, Moroyama, Iruma, Saitama 350-0495, JapanShinya Tanaka, Department of Orthopaedic and Spinal Surgery, Saitama Mediclal University, Morohongo 38, Moroyama, Iruma, Saitama 350-0495, JapanKohei Kawamura, Department of Orthopaedic and Spinal Surgery, Saitama Mediclal University, Morohongo 38, Moroyama, Iruma, Saitama 350-0495, Jap...

Translation and validation of the German version of the Bournemouth Questionnaire for Neck Pain.

Chiropractic and Osteopathy — Wed, 25 Jan 2012 05:00:00 +0100

Conclusions: The German BQN is a valid and reliable outcome measure that has been successfully translated and culturally adapted. It is shorter, easier to use, and more responsive to change than the NDI and NPAD.Key WordsBournemouth Questionnaire; Outcome Assessment; Neck Pain; Chiropractic; Validity of Results (Source: Chiropractic and Osteopathy)

Evaluation of Indirect Decompression of the Lumbar Spinal Canal Following Minimally Invasive Lateral Transpsoas Interbody Fusion: Radiographic and Outcome Analysis

min - Minimally Invasive Neurosurgery — Wed, 25 Jan 2012 05:00:00 +0100

Minim Invasive Neurosurg 2011; 54: 201-206DOI: 10.1055/s-0031-1286334The surgical treatment of lumbar stenosis traditionally includes laminectomy for direct decompression of the spinal canal. Selected patients with spinal stenosis may also require lumbar fusion. Minimally invasive lateral transpsoas interbody fusion has the ability of placing a large interbody cage that can increase disc height and distract the spinal level. The purpose of this study was to examine the concept of indirect decompression of the spinal canal in patients with co-existing lumbar spinal stenosis undergoing lateral transpsoas interbody fusion.We reviewed 25 consecutive spinal stenosis patients with instability undergoing lateral transpsoas interbody fusion without laminectomy. All patients had relevant symptoms o...

Massive Swelling of Surgicel® Fibrillar™ Hemostat after Spinal Surgery. Case Report and a Review of the Literature

min - Minimally Invasive Neurosurgery — Wed, 25 Jan 2012 05:00:00 +0100

We report on a 65-year-old woman who was operated for a high-grade spinal stenosis at the L2-L3 level. Small portions of Surgicel® Fibrillar™ were used to control bleeding from the epidural venous plexus. The immediate postoperative course was uneventful. However, one day after surgery, the patient complained about progressive worsening pain at the operated level. A non-contrast lumbar CT scan showed no evidence of a postoperative hematoma or other complication. MR imaging showed a horseshoe-shaped mass compressing the dural sac at the operated level from posterior and both sides. Because we suspected a postoperative hematoma, the patient was re-operated. No hemorrhage was seen but instead we found large, swollen firm pieces of Surgicel® Fibrillar™ compressing the dural sac. These pi...

Derivation of a Preliminary Clinical Prediction Rule for Identifying a Sub-Group of Patients With Low Back Pain Likely to Benefit From Pilates-Based Exercise.

Physical Therapy — Wed, 25 Jan 2012 05:00:00 +0100

CONCLUSION: These data provide preliminary evidence to suggest that the response to Pilates -based exercise in patients with LBP can be predicted from variables collected from the clinical examination. If subsequently validated in a randomized clinical trial, this prediction rule may be useful to improve clinical decision-making in determining which patients are most likely to benefit from Pilates-based exercise. J Orthop Sports Phys Ther, Epub 25 January 2012. doi:10.2519/jospt.2012.3826. PMID: 22281950 [PubMed - as supplied by publisher] (Source: Physical Therapy)

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Targeting Spinal Long-Term Potentiation as a Basis for Analgesia Recent Developments.

Current Clinical Pharmacology — Wed, 25 Jan 2012 05:00:00 +0100

Authors: Adolph O, Föhr KJ Abstract Recent investigations of pain mechanisms leading to the induction and maintenance of long-term potentiation (LTP) in the spinal cord have identified a huge number of molecular targets that might be appropriate for therapeutically intervention. In this short review we summarize recently published studies investigating drugs that affect LTP in the spinal cord. After providing an overview of spinal pain pathways and of the respective methods for their investigation, molecular targets for possible pharmacological interventions are discussed. PMID: 22283614 [PubMed - as supplied by publisher] (Source: Current Clinical Pharmacology)

Here Today, Gone Tomorrow…and Back Again? A Review of Herbal Marijuana Alternatives (K2, Spice), Synthetic Cathinones (Bath Salts), Kratom, Salvia divinorum, Methoxetamine, and Piperazines.

Journal of Medical Toxicology — Wed, 25 Jan 2012 05:00:00 +0100

Authors: Rosenbaum CD, Carreiro SP, Babu KM Abstract Despite their widespread Internet availability and use, many of the new drugs of abuse remain unfamiliar to health care providers. The herbal marijuana alternatives, like K2 or Spice, are a group of herbal blends that contain a mixture of plant matter in addition to chemical grade synthetic cannabinoids. The synthetic cathinones, commonly called "bath salts," have resulted in nationwide emergency department visits for severe agitation, sympathomimetic toxicity, and death. Kratom, a plant product derived from Mitragyna speciosa Korth, has opioid-like effects, and has been used for the treatment of chronic pain and amelioration of opioid-withdrawal symptoms. Salvia divinorum is a hallucinogen with unique pharmacology that has thera...

One-week and 3-month outcomes after an emergency department visit for undifferentiated musculoskeletal low back pain.

Pain Physician — Tue, 24 Jan 2012 19:48:41 +0100

CONCLUSION: There is substantial short- and longer-term morbidity and ongoing analgesic use among patients who present to an ED with undifferentiated musculoskeletal low back pain. PMID: 22265130 [PubMed - in process] (Source: Pain Physician)

‘We tried to hide in the high grass but they heard my child crying’

MSF News — Tue, 24 Jan 2012 19:27:00 +0100

One recurring characteristic of the attacks in Jonglei State, South Sudan during recent months is their extreme violence. A deeply worrisome pattern is emerging, where people and their scarce resources are deliberately targeted by all the armed groups in this intercommunal violence. These are some of the stories patients have been telling the Médecins Sans Frontières (MSF) staff providing care to people trying to survive the violence. Patient testimony of a 24-year-old woman who was shot in the leg and in the cheek in the attack on Lekwongole on Dec. 27, 2011. Her only daughter, three, was abducted. Our village was one of the first to be attacked. Three women, including me, ran with our children – my own three-year-old daughter and two of their boys who are 10 and 11 years old....

Stem cell therapy 'safe for eye condition'

NHS News Feed — Tue, 24 Jan 2012 17:55:00 +0100

Conclusion This was a small clinical trial that assessed the safety of using stem cell technology to treat one person with Stargardt’s macular dystrophy and one person with dry age-related macular degeneration. Specifically, it looked at the use of retinal cells that had been made from human embryonic stem cells. The primary focus of this research was to see whether this procedure would be safe, not whether it was effective. The researchers found that neither of the patients had problems with abnormal cell growth, tumour formation, graft rejection or any other pathological reaction or safety issues, all of which are potential problems in this type of treatment. The researchers followed the patients over four months but say that further follow-up is needed to observe the long-term effec...

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Kyphoplasty and intra-operative radiotheray, combination of kyphoplasty and intra-operative radiation for spinal metastases: technical feasibility of a novel approach

International Orthopaedics — Tue, 24 Jan 2012 07:53:18 +0100

Conclusions Summarizing Kypho-IORT is technically feasible with an intra-operative risk profile comparable to sole kyphoplasty and a shorter treatment time and hospitalisation for the patients compared to conventional multifraction radiation. Radiation could not be applied in 10% of cases due to technical difficulties. The results of this feasibility study permit further evaluation of this new technique by a dose escalation study which is currently in preparation. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00264-011-1470-9Authors René Schmidt, Department of Orthopedic and Trauma Surgery, University Medical Center Mannheim, Mannheim, GermanyFrederik Wenz, Department of Radiation Oncology, University Medical Center Mannheim, Mannheim, G...

Spine stabilisation exercises in the treatment of chronic low back pain: a good clinical outcome is not associated with improved abdominal muscle function

European Spine Journal — Tue, 24 Jan 2012 07:32:44 +0100

Conclusion Neither baseline lateral abdominal muscle function nor its improvement after a programme of stabilisation exercises was a statistical predictor of a good clinical outcome. It is hence difficult to attribute the therapeutic result to any specific effects of the exercises on these trunk muscles. The association between changes in catastrophising and outcome serves to encourage further investigation on larger groups of patients to clarify whether stabilisation exercises have some sort of “central” effect, unrelated to abdominal muscle function per se. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00586-012-2155-9Authors A. F. Mannion, Spine Center Division, Department of Research and Development, Schulthess Klinik, Lenggha...

Post-traumatic thoracic outlet syndrome

Acta Neurochirurgica — Tue, 24 Jan 2012 07:28:21 +0100

Conclusions The majority of patients suffering from a post-traumatic TOS present a neurogenic, usually subjective syndrome. Prompt therapeutic management is necessary, addressing both physical and psychological complaints. Most patients are cured or well improved by conservative and/or surgical treatment. Content Type Journal ArticleCategory Clinical ArticlePages 1-10DOI 10.1007/s00701-011-1269-xAuthors Annie Dubuisson, Department of Neurosurgery, CHU Liège, Domaine Universitaire du Sart Tilman, B 35, 4000 Liège, BelgiumCatherine Lamotte, Department of Physical Therapy, CHU, Liège, BelgiumMarguerite Foidart-Dessalle, Department of Physical Therapy, CHU, Liège, BelgiumMinh Nguyen Khac, Department of Neurosurgery, CHU Liège, Domaine Universitaire du Sart Tilman, ...

An evaluation of contrast medium spread on caudal epidurography with the needle positioned toward the affected side in patients with unilateral lumbosacral radiculopathy

Skeletal Radiology — Tue, 24 Jan 2012 06:52:07 +0100

Conclusions When a needle was intentionally inserted toward the side with radiculopathy, the spread of contrast medium and number of delineated roots tended to be greater on the side with the needle, compared with those on the opposite side. However, the pattern of contrast medium spread in the sacral epidural space varied and some patients even had greater spread on the opposite side. Content Type Journal ArticleCategory Technical ReportPages 1-6DOI 10.1007/s00256-011-1354-5Authors Jae Hoon Lee, Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, South KoreaDuck Mi Yoon, Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute,...

Identifying factors relevant in the assessment of return-to-work efforts in employees on long-term sickness absence due to chronic low back pain: a focus group study

BMC Public Health - Latest articles — Tue, 24 Jan 2012 05:00:00 +0100

Conclusions: This focus group study shows that 19 factors may be relevant to RTW-ES in sick-listed employees with CLBP. Providing these results to professionals assessing RTW-ES might contribute to a more transparent and systematic approach. Considering the importance of the quality of the RTW process, optimizing the RTW-ES assessment is essential. (Source: BMC Public Health - Latest articles)

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Genetic marking and characterization of Tac2-expressing neurons in the central and peripheral nervous system

Molecular Brain — Tue, 24 Jan 2012 05:00:00 +0100

Conclusions: Tac2-Cre mice are a useful tool to mark specific subsets of neurons in the sensory ganglia, the dorsal spinal cord, and the brain. These mice can also be used for future genetic manipulations to study the functions of Tac2-expressing neurons or the functions of genes expressed in these neurons. (Source: Molecular Brain)

Triggers for an episode of sudden onset low back pain: study protocol

BMC Musculoskeletal Disorders — Tue, 24 Jan 2012 05:00:00 +0100

This study uses a case-crossover design. One thousand adults with a sudden onset of low back pain presenting to primary care clinicians will be recruited. Basic demographic and clinical information including exposure to putative triggers will be collected using a questionnaire. These triggers include exposure to hazardous manual tasks, physical activity, a slip/trip or fall, consumption of alcohol, sexual activity, being distracted, and being fatigued or tired. Exposures in the case window (0-2 hours from the time when participants first notice their back pain) will be compared to exposures in two control time-windows (one 24-26 hours and another 48-50 hours before the case window).DiscussionThe completion of this study will provide the first-research based estimates of the increase in ris...

Fatigue level in spinal cord injury AIS D community ambulatory subjects

Spinal Cord — Tue, 24 Jan 2012 05:00:00 +0100

Authors: O Freixes, M E Rivas, P E Agrati, V Bochkezanian, S V Waldman & L E Olmos (Source: Spinal Cord)

Targeting Spinal Long-Term Potentiation as a Basis for Analgesia Recent Developments.

Current Clinical Pharmacology — Tue, 24 Jan 2012 05:00:00 +0100

Authors: Adolph O, Föhr KJ Abstract Recent investigations of pain mechanisms leading to the induction and maintenance of long-term potentiation (LTP) in the spinal cord have identified a huge number of molecular targets that might be appropriate for therapeutically intervention. In this short review we summarize recently published studies investigating drugs that affect LTP in the spinal cord. After providing an overview of spinal pain pathways and of the respective methods for their investigation, molecular targets for possible pharmacological interventions are discussed. PMID: 22280326 [PubMed - as supplied by publisher] (Source: Current Clinical Pharmacology)

Statin Use and Musculoskeletal Pain Among Adults With and Without Arthritis

The American Journal of Medicine — Mon, 23 Jan 2012 23:45:00 +0100

Conclusion: In this population-based study, statin use was associated with a higher prevalence of musculoskeletal pain, particularly in the lower extremities, among individuals without arthritis. Evidence that statin use was associated with musculoskeletal pain among those with arthritis was lacking. (Source: The American Journal of Medicine)

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Gender Differences in Modifying Lumbopelvic Motion during Hip Medial Rotation in People with Low Back Pain

Advances in Pharmacological Sciences — Mon, 23 Jan 2012 18:36:31 +0100

Reducing increased or early lumbopelvic motion during trunk or limb movements may be an important component of low back pain treatment. The ability to reduce lumbopelvic motion may be influenced by gender. The purpose of the current study was to examine the effect of gender on the ability of people with low back pain to reduce lumbopelvic motion during hip medial rotation following physical therapy treatment. Lumbopelvic rotation and hip rotation before the start of lumbopelvic rotation were assessed pre- and posttreatment for 16 females and 15 males. Both men and women decreased lumbopelvic rotation and completed more hip rotation before the start of lumbopelvic rotation post-treatment compared to pre-treatment. Men demonstrated greater lumbopelvic rotation and completed less hip rotation...

Neck pain: manipulation of your neck and upper back leads to quicker recovery.

Physical Therapy — Mon, 23 Jan 2012 15:30:06 +0100

Authors: Abstract Neck pain is very common and fortunately resolves quickly in most individuals. However, in certain cases neck pain can last longer and result in chronic pain, limited neck motion, and disability. In fact, chronic neck pain is the second leading cause of workers' compensation claims in the United States. Treatments that can quickly reduce pain, increase motion, and improve the ability of the muscles to protect the neck may help decrease long-term disability associated with neck pain. A variety of manual therapy treatments are currently used to manage neck pain. These treatments include mobilization, which slowly and repeatedly moves the neck joints and muscles, and manipulation, which delivers a single, small, quick movement to the joints and muscles. A research r...

A qualitative study on the role of cultural background in patients' perspectives on rehabilitation

BMC Musculoskeletal Disorders — Mon, 23 Jan 2012 05:00:00 +0100

Conclusions: LBP rehabilitation can be improved by addressing the following points. Early management of LBP should be activity-centred instead of pain-centred. It is mandatory to implement return to work management early, including return to adapted work, to improve rehabilitation for patients. Rehabilitation has to start when patients have been off work for three months. Using interpreters more frequently would improve communication between health professionals and patients, and reduce misunderstandings about treatment procedures. Special emphasis must be put on the process of goal-formulation by spending more time with patients in order to identify barriers to goal attainment. Information on the return to work process should also include the financial aspects of unemployment and disabili...

Effect of MRI on Treatment Results or Decision Making in Patients With Lumbosacral Radiculopathy Referred for Epidural Steroid Injections: A Multicenter, Randomized Controlled Trial [Original Investigation]

Archives of Internal Medicine — Mon, 23 Jan 2012 05:00:00 +0100

Conclusion Magnetic resonance imaging does not improve outcomes in patients who are clinical candidates for ESI and has only a minor effect on decision making. Trial Registration clinicaltrials.gov Identifier: NCT00826124 (Source: Archives of Internal Medicine)

Predictors of Headache Before, During, and After Pregnancy: A Cohort Study.

Headache — Mon, 23 Jan 2012 05:00:00 +0100

Conclusions.- A history of headache prior to pregnancy is a strong predictor of headache during and after pregnancy, the latter independent of but compounded by spinal injection. Physicians should attend to prior headache history when making decisions about pain management during and after childbirth. As the lack of formal International Classification of Headache Disorders, 2nd Edition (ICHD-II), headache diagnoses is a limitation of this study, future longitudinal studies should replicate the present design while including headache subtyping consistent with ICHD-II nosology. PMID: 22268840 [PubMed - as supplied by publisher] (Source: Headache)

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Orthodontic anchoring techniques and its influence on pain, discomfort, and jaw function--a randomized controlled trial

The European Journal of Orthodontics — Mon, 23 Jan 2012 05:00:00 +0100

The aim of this trial was to evaluate and compare perceived pain, discomfort, and jaw function impairment between orthodontic treatments combined with skeletal anchorage and treatment using conventional anchorage with headgear or transpalatal bar. A total of 120 adolescent patients in order to start orthodontic treatment were consecutively recruited and randomized into three groups with different anchorage. Group A underwent installation of a skeletal anchorage (Onplant or Orthosystem implant), group B received headgear, and group C a transpalatal bar. Questionnaires were used to assess pain intensity, discomfort, analgesic consumption, and jaw function impairment from baseline to the end of treatment. Pain scores overall peaked on day 2 and were almost back to baseline on day 7. The site ...

What Can Parents Do To Keep Their Children Safe on Playgrounds?

PediatricEducation.org — Mon, 23 Jan 2012 00:50:28 +0100

Discussion About 200,000 children are injured each year on playgrounds costing an estimated 1.2 billion dollars. Most of the playground injuries are at schools and daycare centers and gender rates and age rates depend on the study. More injuries occur in the summer months. Rates of severe injuries varies depending on classification and the specific study conducted. Fractures, lacerations, contusion/abrasion, and strains/sprains all are common injuries. Falls contribute to about 80% of injuries. Between 1990-2000, 147 children died from playground injuries – 82 from strangulation and 31 from falls. The number decreased from 2001-2008 to 40 deaths with 27 due to strangulation and 7 due to head injury. Climbing equipment and swings cause the most equipment-related injures. Learning Poin...

Old method to ease back pain now popular

Health News - UPI.com — Sun, 22 Jan 2012 21:23:26 +0100

MIAMI, Jan. 22 (UPI) -- A little known European holistic technique that relieves back pain, dating back to the 1890s, is gaining popularity in the United States, fitness experts say. (Source: Health News - UPI.com)

New understanding of chronic pain

ScienceDaily Headlines — Sun, 22 Jan 2012 20:24:24 +0100

Millions of people worldwide suffer from a type of chronic pain called neuropathic pain, which is triggered by nerve damage. Precisely how this pain persists has been a mystery, and current treatments are largely ineffective. But scientists, using a new approach known as metabolomics, have now discovered a major clue: dimethylsphingosine (DMS), a small-molecule byproduct of cellular membranes in the nervous system. In their new study, the scientists found that DMS is produced at abnormally high levels in the spinal cords of rats with neuropathic pain and appears to cause pain when injected. The findings suggest inhibiting this molecule may be a fruitful target for drug development. (Source: ScienceDaily Headlines)

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[Sacroiliitis or pseudosacroiliitis?]

Der Radiologe — Sat, 21 Jan 2012 05:00:00 +0100

Authors: Schueller-Weidekamm C, Schueller G Abstract CLINICAL/METHODICAL ISSUE: When the presence of seronegative spondyloarthropathy is unrecognized there can be a delay in achieving an accurate diagnosis, as the typical inflammatory low back pain is similar to that found in degenerative diseases of the lumbosacral spine and the sacroiliac joints. Thus, seronegative spondyloarthropathy is often misinterpreted as a degenerative disease. The initial radiography of the sacroiliac joints is often normal which results in a delay in diagnosis of sacroiliitis of approximately 3-7 years. STANDARD RADIOLOGICAL METHODS: This illustrates the significance of an adequate imaging method for the early detection of sacroliliitis. METH...

Claimant Petitions For En Banc Review Over 8th Circuit Finding

LexisNexis® Mealey's™ Disability Insurance Legal News — Sat, 21 Jan 2012 00:05:53 +0100

ST. LOUIS - A claimant with severe back pain on Dec. 20 filed a petition for en banc review with the Eighth Circuit U.S. Court of Appeals, asking for his appeal to be heard by all the justices despite a ruling last month by an Eighth Circuit panel upholding a disability insurer's reliance on record reviews and video surveillance in its decision to deny benefits (Troy J. Daigle v Hartford Life and Accident Insurance Co., No. 11-1847, 8th Cir.; 2011 U.S. App. LEXIS 24349). Full story on lexis.com (Source: LexisNexis® Mealey's™ Disability Insurance Legal News)

What is Recovery LIke After Tubal Reversal Surgery?

Tubal Ligation Reversal News — Sat, 21 Jan 2012 00:00:00 +0100

One of the first concerns anyone might have prior to surgery is whether the procedure will be painful. On the Tubal Reversal Message Board, 'SoInLove' posts this question: "I am 29 and really considering TR I had my TL a little over 6 years ago and have been regretting it since. Can anyone tell me what the recovery is like?" Another message board member, 'lynngirl1976' responds, "Recovery was easier than the tubal ligation. I only needed Ibprofen for uncomfortable feeling." At Chapel Hill Tubal Reversal Center, Dr. Berger and Dr. Monteith, the world's foremost tubal reversal doctors, have developed special surgical techniques that minimize postoperative pain. Based on a pain score of 0 - 10 (with zero meaning no pain and 10 the worst imaginable), tubal reversal patients at Chapel Hill Tuba...

One-Week and 3-Month Outcomes After an Emergency Department Visit for Undifferentiated Musculoskeletal Low Back Pain

Annals of Emergency Medicine — Fri, 20 Jan 2012 19:16:32 +0100

Conclusion: There is substantial short- and longer-term morbidity and ongoing analgesic use among patients who present to an ED with undifferentiated musculoskeletal low back pain. (Source: Annals of Emergency Medicine)

Radiographic and clinical results of posterior dynamic stabilization for the treatment of multisegment degenerative disc disease with a minimum follow-up of 3 years

Archives of Orthopaedic and Trauma Surgery — Fri, 20 Jan 2012 07:04:39 +0100

Conclusion In conclusion, Dynesys is an acceptable alternative to PLIF for the treatment of multisegment lumbar disease. Content Type Journal ArticleCategory Orthopaedic SurgeryPages 1-7DOI 10.1007/s00402-012-1460-4Authors Shang-Won Yu, Department of Orthopedic Surgery, E-Da Hospital/I-Shou University, 1, E-Da Road, Jiau-Shu Tsuen, Yan-Chau Shiang, 824, Kaohsiung County, Taiwan, Republic of ChinaCheng-Yo Yen, Department of Orthopedic Surgery, E-Da Hospital/I-Shou University, 1, E-Da Road, Jiau-Shu Tsuen, Yan-Chau Shiang, 824, Kaohsiung County, Taiwan, Republic of ChinaChin-Hsien Wu, Department of Orthopedic Surgery, E-Da Hospital/I-Shou University, 1, E-Da Road, Jiau-Shu Tsuen, Yan-Chau Shiang, 824, Kaohsiung County, Taiwan, Republic of ChinaFeng-Chen Kao, Department of...

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Activation of TRPV1 by capsaicin induces functional Kinin B1 receptor in rat spinal cord microglia

Journal of Neuroinflammation — Fri, 20 Jan 2012 05:00:00 +0100

Conclusion: This study highlights a new mechanism for B1R induction via TRPV1 activation and establishes a link between these two pro-nociceptive receptors in inflammatory pain. (Source: Journal of Neuroinflammation)

Clinical course, characteristics and prognostic indicators in patients presenting with back and leg pain in primary care. The ATLAS study protocol.

BMC Musculoskeletal Disorders — Fri, 20 Jan 2012 05:00:00 +0100

DiscussionThis prospective clinical observational cohort will combine self-reported data, comprehensive clinical and MRI assessment, together with qualitative enquiries, to describe the course, health care usage, patients' experiences and prognostic indicators in an adult population presenting in primary care with LBP and leg pain with or without nerve root involvement. (Source: BMC Musculoskeletal Disorders)

Spondylosis

About.com Eating Disorders — Fri, 20 Jan 2012 05:00:00 +0100

is the word used to describe arthritis of the spine. Wear-and-tear arthritis, also called osteoarthritis, is a common cause of back pain. When osteoarthritis occus in the spine, the word used to descibe this condition is spondylosis. (Source: About.com Eating Disorders)

Cost-effectiveness of a classification-based system for sub-acute and chronic low back pain

European Spine Journal — Thu, 19 Jan 2012 07:01:31 +0100

Conclusion The classification-based treatment approach as used in this study was not cost-effective in comparison with usual physical therapy care in a population of patients with sub-acute and chronic LBP. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00586-011-2144-4Authors Adri T. Apeldoorn, Department of Epidemiology and Biostatistics and the EMGO+ Institute for Health and Care Research, VU University Medical Centre, Van der Boechorststraat 7, Amsterdam, 1081 BT The NetherlandsJudith E. Bosmans, Department of Health Sciences and the EMGO+ Institute for Health and Care Research, Faculty of Earth and Life Sciences, VU University Amsterdam, Amsterdam, The NetherlandsRaymond W. Ostelo, Department of Epidemiology and Biostatistics and the...

The Role of Exercise and Types of Exercise in the Rehabilitation of Chronic Pain: Specific or Nonspecific Benefits

Current Pain and Headache Reports — Thu, 19 Jan 2012 06:58:50 +0100

This article summarizes the types of exercise in the rehabilitation of chronic pain patients and provides practical recommendations for the clinician based on empirical and clinical experience. This safe, cost-free, nonpharmacologic way of managing pain has been found to reduce anxiety and depression, improve physical capacity, increase functioning and independence, and reduce morbidity and mortality. Content Type Journal ArticleCategory Psychiatric Management of Pain (MR Clark, Section Editor)Pages 1-9DOI 10.1007/s11916-012-0245-3Authors Amy Burleson Sullivan, Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic, Mail Code U10, 9500 Euclid Avenue, Cleveland, OH 44195, USAJudith Scheman, Neurological Center for Pain, Cleveland Clinic, Mail Code C21, 9500 ...

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Unilateral hyperplasia of lamina and spinous process of C6 vertebra: case report

Surgical and Radiologic Anatomy — Thu, 19 Jan 2012 06:54:53 +0100

We report a 20-year-old male patient who was admitted to our emergency clinic after a traffic accident and who suffered from neck pain. Radiographic examination of the cervical spine showed hypertrophy of the left lamina and hypertrophy and elongation of the left spinous process of the sixth cervical vertebra (C6). A computed tomography scan revealed the associated schisis of the spinous process at the same level. Magnetic resonance imaging scan demonstrated no abnormality of the neural elements. The patient underwent a surgical operation due to persistent neck pain and the local aesthetic abnormality. Content Type Journal ArticleCategory Anatomic VariationsPages 1-4DOI 10.1007/s00276-012-0934-yAuthors Burak Kazanci, Neurosurgery Clinic, Ministry of Health, Sevket Yilmaz Educati...

Wound infiltration with local anesthetics for post‐operative pain relief in lumbar spine surgery: a systematic review

Acta Anaesthesiologica Scandinavica — Thu, 19 Jan 2012 05:00:00 +0100

ConclusionInterpretation of the results was difficult because of diversity of the studies. However, clinical significance was in general questionable, with only a few trials showing a small or a modest reduction in pain intensity, which was observed mainly immediately after the operation. Similarly, although more frequently observed, only a minor and probably not clinically relevant reduction in opioid consumption was shown. (Source: Acta Anaesthesiologica Scandinavica)

Targeted treatment in primary care for low back pain: the treatment system and clinical training programmes used in the IMPaCT Back study (ISRCTN 55174281)

Family Practice — Thu, 19 Jan 2012 05:00:00 +0100

Discussion. This paper describes in detail the IMPaCT Back study’s subgrouping for targeted treatment system and the training and mentoring packages aimed at equipping clinicians to deliver it, within the IMPaCT Back study. Study registration. ISRCTN55174281. (Source: Family Practice)

The significance of health anxiety and somatization in care-seeking for back and upper extremity pain

Family Practice — Thu, 19 Jan 2012 05:00:00 +0100

Conclusion. The study implies that prevention of back pain and upper extremity pain requires different strategies and that gender and health anxieties should be taken into account. (Source: Family Practice)

Concomitant Reconstruction of Infrarenal Aorta and Inferior Vena Cava After En Bloc Resection of Retroperitoneal Rhabdomyosarcoma

Vascular and Endovascular Surgery — Thu, 19 Jan 2012 05:00:00 +0100

We describe a 23-year-old male diagnosed with PRMS in 2008, previously treated with right orchiectomy, chemotherapy, and radiation, who presented with new onset of lower back pain. Computed tomography (CT) scan revealed a 4.8 x 4.2 cm mass involving both the infrarenal aorta and the IVC. We resected the tumor en bloc with in situ reconstruction of the aorta utilizing a Dacron graft and the IVC with a bovine pericardium roll graft. His postoperative period was uneventful, and he was discharged on postoperative day 6 in stable condition. At 2-month follow-up, the patient recovered well from the surgery, patent grafts on CT scan with no clinical signs of lower extremity ischemia or edema, and he continues to receive cycles of chemotherapy. (Source: Vascular and Endovascular Surgery)

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Reversible, Hyperacute Allodynia After Evacuation of a Cervical Epidural Hematoma

Journal of Pain and Symptom Management — Thu, 19 Jan 2012 03:24:50 +0100

Hyperacute allodynia, that is, pain elicited by nonpainful stimuli, after spinal cord injury, with secondary disappearance, is exceptional. Only a handful of cases are on record. (Source: Journal of Pain and Symptom Management)

Progressive Weakness and Numbness With a Long History of Back PainProgressive Weakness and Numbness With a Long History of Back Pain

Medscape Today Headlines — Wed, 18 Jan 2012 16:33:40 +0100

A 44-year-old man is evaluated for a 6-month history of progressive bilateral lower extremity numbness and weakness and a 4-year history of back pain. What is the diagnosis? Medscape (Source: Medscape Today Headlines)

Single-stage anterior debridement and fusion with autografting and internal fixation for pyogenic lumbar spondylodiscitis

Archives of Orthopaedic and Trauma Surgery — Wed, 18 Jan 2012 07:00:47 +0100

Conclusion Based on the limited population studied, it suggested that this technique may be a safe and effective operative procedure for appropriate pyogenic lumbar spondylodiscitis in patients. Content Type Journal ArticleCategory Orthopaedic SurgeryPages 1-7DOI 10.1007/s00402-011-1451-xAuthors Xiang Wang, Department of Orthopaedics, The First Affiliated Hospital of Medical School of Zhejiang University, 79 Qingchun Road, Hangzhou, ChinaJianshen Zhou, Department of Orthopaedic Surgery, The First Affiliated Hospital of Bengbu Medical College, 287 ChangHuai Road, Bengbu, Anhui, ChinaChangchun Zhang, Department of Orthopaedic Surgery, The First Affiliated Hospital of Bengbu Medical College, 287 ChangHuai Road, Bengbu, Anhui, ChinaZhenhua Liu, Department of Orthopaedic ...

Zyga replaces co-founder with med-tech vet Bullock as CEO

bizjournals.com Health Care:Physician Practices headlines — Tue, 17 Jan 2012 11:35:29 +0100

Jim Bullock, who has led two Twin Cities companies that eventually were sold to med-tech giants, has been named CEO of Zyga Technology Inc., which makes a device for treating lower back pain. Bullock replaces Bob Assell, who co-founded Minneapolis-based Zyga in March 2008. Assell is now Zyga's chief technology officer. Bullock has been serving as CEO of Plymouth-based Atritech Inc. since August 2005. The company announced a year ago that Boston Scientific Corp. (NYSE: BSX) was buying Atritech for $375 million... (Source: bizjournals.com Health Care:Physician Practices headlines)

Multiple brown tumors causing spinal cord compression in association with secondary hyperparathyroidism

International Urology and Nephrology — Tue, 17 Jan 2012 07:17:23 +0100

Conclusion Differential diagnosis of sudden neurologic deficits and paraplegia in renal patients with secondary HPPT must consider the possibility of brown tumor. Content Type Journal ArticleCategory Nephrology – Case ReportPages 1-4DOI 10.1007/s11255-012-0123-2Authors Sônia M. H. A. Araújo, Department of Internal Medicine, Federal University of Ceará, Rua Professor Costa Mendes, no 2609, Fortaleza, CE CEP 60430-040, BrazilVeralice M. S. Bruin, Department of Internal Medicine, Federal University of Ceará, Rua Professor Costa Mendes, no 2609, Fortaleza, CE CEP 60430-040, BrazilAndrew S. Nunes, Department of Internal Medicine, Federal University of Ceará, Rua Professor Costa Mendes, no 2609, Fortaleza, CE CEP 60430-040, BrazilEduardo N. S. Pereira, Department of...

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Modic type I change may predict rapid progressive, deforming disc degeneration: a prospective 1-year follow-up study

European Spine Journal — Tue, 17 Jan 2012 07:07:20 +0100

Conclusion Endplate deformation, decreasing disc height and change of disc signal intensity appear essential features of accelerated degenerative process associated with M1. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00586-012-2147-9Authors Liisa Kerttula, Department of Radiology, Helsinki University Central Hospital, Topeliuksenkatu 5, HUS, 00029 Helsinki, FinlandKatariina Luoma, Department of Radiology, Helsinki University Central Hospital, Topeliuksenkatu 5, HUS, 00029 Helsinki, FinlandTapio Vehmas, Institute of Occupational Health, Helsinki, FinlandMats Grönblad, Departments of Physical Medicine and Rehabilitation, Helsinki and Uudenmaa District University Hospitals, Helsinki, FinlandEeva Kääpä, Departments of Physical Medicine...

Qualitative exploration of psychological factors associated with spinal cord stimulation outcome.

Chronic Illness — Tue, 17 Jan 2012 05:00:00 +0100

CONCLUSION: The findings provide context for the patients' experience of SCS. This research suggests that improved preparation prior to SCS including information provision, CBT and contact with expert patients may be of value. PMID: 22253294 [PubMed - as supplied by publisher] (Source: Chronic Illness)

The Analgesic Activity of Intrathecal Tianeptine, an Atypical Antidepressant, in a Rat Model of Inflammatory Pain.

Anesthesia and Analgesia — Tue, 17 Jan 2012 05:00:00 +0100

Conclusions:Intrathecally administered tianeptine effectively relieved inflammatory pain in rats. The serotonergic system is related to the activity of tianeptine for facilitated pain at the spinal level. Adrenergic transmission is also involved in tianeptine-induced analgesia for both facilitated and acute pain. The combination of tianeptine and cyclooxygenase-2 inhibitor may provide additional benefits for the management of inflammatory pain. PMID: 22253265 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)

Does Daily Exposure to Whole-Body Vibration and Mechanical Shock Relate to the Prevalence of Low Back and Neck Pain in a Rural Workforce?

Annals of Occupational Hygiene — Mon, 16 Jan 2012 05:00:00 +0100

Conclusions: Knowledge of these findings will be valuable information for those who teach and advise on safe driving techniques for such vehicles in the rural workplace where reduction of physical exposures and injury rates is of high importance. (Source: Annals of Occupational Hygiene)

New Group to Set Priorities for Medical Effectiveness Research

RWJF News Digest - Quality/Equality — Mon, 16 Jan 2012 05:00:00 +0100

More than two years ago, studies found that injection of medical cement into compression fractures of the spine produced no better pain relief than "sham" injections. (Source: RWJF News Digest - Quality/Equality)

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Antinociceptive Effects of Eugenol Evaluated in a Monoiodoacetate‐induced Osteoarthritis Rat Model

Phytotherapy Research — Mon, 16 Jan 2012 05:00:00 +0100

The aim of the present study was to evaluate whether eugenol, the main constituent of clove oil, has the capacity to provide analgesia in the monoiodoacetate‐induced rat model of osteoarthritis. Animals (n = 6/group) received either eugenol (20 or 40 mg/kg) or a vehicle by gavage. Daily administrations were initiated 2 days post osteoarthritis induction and continued for the duration of the study (4 weeks). Gait analysis was performed using the CatWalk method and secondary mechanical allodynia was assessed with von Frey filaments. Selected spinal cord peptides (substance P, calcitonin gene‐related peptide and dynorphin) were quantified by mass spectrometry. Significant changes were identified in dynamic gait parameters (swing speed, swing phase duration and duty cycle) of the...

Professional driving and prolapsed lumbar intervertebral disc diagnosed by magnetic resonance imaging - a case-control study.

Scandinavian Journal of Work, Environment and Health — Mon, 16 Jan 2012 05:00:00 +0100

CONCLUSIONS: WBV may be a cause of LBP but it was not associated with PID or nerve root entrapment in this study. PMID: 22249859 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Work, Environment and Health)

A series of case studies: practical methodology for identifying antinociceptive multi-target drugs.

Drug Discovery Today — Mon, 16 Jan 2012 05:00:00 +0100

Authors: Pang MH, Kim Y, Jung KW, Cho S, Lee DH Abstract Since the introduction of drug discovery based on single targets, the number of newly developed drugs has steadily declined, and the reliablility of the current drug-discovery paradigm has been unceasingly questioned. As an alternative, an emerging approach pursuing multi-targeting drugs has arisen to reflect multifactorial diseases caused by the complex networks of various mechanisms. The purpose of this paper is to review multi-target drugs and introduce our progress in establishing a practical methodology for identifying antinociceptive multi-target drugs. We have adopted a system of ex vivo efficacy screening using long-term potentiation in rat spinal cord as a surrogate biomarker for neuropathic pain. A bait-target appro...

[Report] Erasure of a Spinal Memory Trace of Pain by a Brief, High-Dose Opioid Administration

Science: Current Issue — Sun, 15 Jan 2012 06:42:26 +0100

Opioid administration turns down a pain amplifier by reversing synaptic long-term potentiation in spinal nociceptive pathways.Authors: Ruth Drdla-Schutting, Justus Benrath, Gabriele Wunderbaldinger, Jürgen Sandkühler (Source: Science: Current Issue)

Effectiveness of Teriparatide in Postmenopausal Women with Osteoporosis and Glucocorticoid Use: 3-Year Results from the EFOS Study.

J Rheumatol — Sun, 15 Jan 2012 05:00:00 +0100

CONCLUSION: Postmenopausal women with severe osteoporosis receiving GC, who were treated with teriparatide for up to 18 months, showed a reduced incidence of clinical fractures during the third year while receiving sequential osteoporosis treatments compared with the first 6 months, together with reduced back pain and improved HRQOL. Our results should be interpreted in the context of an uncontrolled observational study in a routine clinical setting. PMID: 22247365 [PubMed - as supplied by publisher] (Source: J Rheumatol)

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Assessment of Preclinical Atherosclerosis in Patients with Ankylosing Spondylitis.

J Rheumatol — Sun, 15 Jan 2012 05:00:00 +0100

CONCLUSION: AS is associated with an increased risk of atherosclerosis independent of traditional risk factors. Disease activity, functional and mobility limitations, structural damage, and inflammation are the most incriminated risk factors. PMID: 22247364 [PubMed - as supplied by publisher] (Source: J Rheumatol)

OnQ Pain Pump Versus Epidural for Postoperative Analgesia in a Pediatric Population

Journal of Surgical Research — Sat, 14 Jan 2012 22:29:59 +0100

Introduction: The On-Q® pain pump provides a continuous infusion of regional anesthesia for management of postoperative pain. Several studies have evaluated its use in adult patients, but little is known about its effectiveness in children. the objective of this study was to assess the efficacy and outcomes of pediatric patients treated with the On-Q® pump, and compare it to conventional epidural use in the postoperative period. Methods: We evaluated all patients in our hospital, from 2005-2008 who underwent a surgical procedure and received either an epidural infusion or On-Q® pump postoperatively. 192 patients met criteria, 124 epidural and 64 On-Q® (4 patients received both therapies and were excluded). Patients were sub-categorized by procedure type, abdominal, thoracic, or other (...

Novel Technique for Gallbladder Retraction During Single, Incision Cholecystectomy: Initial Experience

Journal of Surgical Research — Sat, 14 Jan 2012 22:29:48 +0100

Conclusions: In this initial experience, the use of this novel retraction device demonstrated to be reliable, safe and easy to use. the retraction device allows the surgeon to perform the cholecystectomy within acceptable operative time, and no added complications. the advantages of this new device are that it is versatile, reusable, reduces the number of incisions, and is re-adjustable. in addition, more retractors can be added if necessary. the adaptability of this novel device will potentially broaden the range of procedures that can be performed through a single-incision. (Source: Journal of Surgical Research)

Clinical, radiological, histological and retrieval findings of Activ-L and Mobidisc total disc replacements: a study of two patients

European Spine Journal — Sat, 14 Jan 2012 16:42:09 +0100

Conclusion Although wear was unrelated to the reason for revision, this study demonstrates the presence of UHMWPE particles and inflammatory cells in second generation TDR. Long-term follow-up after TDR is indicated for monitoring wear and implant status. Content Type Journal ArticleCategory Case ReportPages 1-8DOI 10.1007/s00586-011-2141-7Authors Shennah Austen, Department of Orthopaedic Surgery, Maastricht University Medical Center, P.O. Box 5800, 6202 AZ Maastricht, The NetherlandsIlona M. Punt, Department of Orthopaedic Surgery, Maastricht University Medical Center, P.O. Box 5800, 6202 AZ Maastricht, The NetherlandsJack P. M. Cleutjens, Department of Pathology, Research School CARIM, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The NetherlandsPaul C. ...

Stereotactic radiosurgery for primary and metastatic sarcomas involving the spine

Journal of Neuro-Oncology — Sat, 14 Jan 2012 16:41:35 +0100

Abstract The treatment for spinal sarcomas is difficult due to inadequate surgical margin and an inability to deliver high dose radiation. Advanced technology of stereotactic radiosurgery (SRS) enabled higher biological effective doses of radiation to be delivered to spinal sarcomas by hypofractionation method. The authors evaluated local control rate following SRS for primary and metastatic spinal sarcomas. Thirty-two spinal sarcomas (10 primary tumors, 22 metastatic tumors) in 27 patients were treated by SRS from November 2002 to September 2009. Patients were assessed for pain status, neurological status and radiological response by regular follow-up. Overall survival and local progression-free survival were calculated and prognostic factors were sought. Median tumor vol...

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Minimally invasive thoracolumbar corpectomy and reconstruction.

Orthopedics — Sat, 14 Jan 2012 15:24:05 +0100

This article describes our technique for performing minimally invasive surgical thoracolumbar corpectomy and reconstruction. Twenty-five consecutive patients at a single institution were treated between 2006 and 2010 for a variety of diagnoses including tumors, infections, and trauma. Treatment variables, including operating time, estimated blood loss, number of levels treated, and complications, were collected, as were visual analog scale (VAS) scores for pain.Surgical times (mean, 188.5 minutes) and blood loss (mean, 423 mL) reflect a significant improvement over standard open corpectomy procedures. More than 60% of patients did not need blood products after the corpectomy procedure because substantial blood loss encountered during an open exposure to the spine was obviated. Similarly, o...

Nocardia Spinal Epidural Abscess: 14-year Follow-up.

Orthopedics — Sat, 14 Jan 2012 15:24:05 +0100

This article describes an immunocompetent patient with a spinal abscess that developed from Nocardia asteroides. Nocardia is a rare etiology for spinal abscesses, especially in immunocompetent patients. Nocardia usually affects the lungs and brain of immunocompromised individuals. Few reports of Nocardia involving bones or the spine have been published.The patient had a history of chronic back pain and had several procedures to alleviate the pain. In August 1997, the patient had an epidural block and a subsequent infection that was treated with antibiotics. In October 1997, she developed increasing back pain greater than her baseline chronic low back pain. Additional presenting symptoms were fever, chills, and nausea. On admission, magnetic resonance imaging (MRI) revealed an epidural absc...

Opioids erase memory traces of pain

ScienceDaily Headlines — Sat, 14 Jan 2012 01:49:49 +0100

Medical researchers have discovered a previously unknown effect of opioids. The study shows that opioids not only temporarily relieve pain, but at the right dose can also erase memory traces of pain in the spinal cord and therefore eliminate a key cause of chronic pain. (Source: ScienceDaily Headlines)

Predictors of outcome after surgery with disc prosthesis and rehabilitation in patients with chronic low back pain and degenerative disc: 2-year follow-up

European Spine Journal — Fri, 13 Jan 2012 16:57:34 +0100

Conclusions Shorter duration of LBP, Modic type I or II changes and low FABQ-W were the best predictors of success after treatment with disc prosthesis, while high ODI, low distress and not using narcotics daily predicted better outcome of rehabilitation. Low FABQ-W and working predicted working at follow-up. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00586-011-2145-3Authors Christian Hellum, Department of Orthopaedics, Oslo University Hospital, University of Oslo, Kirkevn 166, 0407 Oslo, NorwayLars Gunnar Johnsen, National Centre for Diseases of the Spine, Trondheim University Hospital, Trondheim, NorwayØyvind Gjertsen, Department of Radiology, Oslo University Hospital, University of Oslo, Oslo, NorwayLinda Berg, Department of Radi...

TRPV1s in Action

Neuromics — Fri, 13 Jan 2012 15:21:00 +0100

Our TRPV1s continue to be widely used and published. This recent publication features use out TRPV1-C guinea pig polyclonal for immunohistochemistry and TRPV1-mouse specific for Western Blotting: Sarah E. Canetta, Edlira Luca, Elyse Pertot, Lorna W. Role, David A. Talmage. Type III Nrg1 Back Signaling Enhances Functional TRPV1 along Sensory Axons Contributing to Basal and Inflammatory Thermal Pain Sensation. PLoS ONE 6(9): e25108. doi:10.1371/journal.pone.0025108...IHC: TRPV1 (guinea pig, 1:1000, GP14100 Neuromics); WB: TRPV1 (rabbit, 1:1000, RA14113 Neuromics).Figure. Sensory axons, but not soma, from Type III Nrg1+/− mice show reduced capsaicin responsiveness compared to axons from WT mice. (A) Representative traces of intracellular calcium along sensory axons in response to 1 µM caps...

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Fibronectin Inhibits Chronic Pain Development after Spinal Cord Injury

Journal of Neurotrauma — Fri, 13 Jan 2012 14:58:23 +0100

Journal of Neurotrauma , Vol. 0, No. 0. (Source: Journal of Neurotrauma)

Tucson Chiropractor launches new website for enhanced patient communication

Healthcare IT News Press Releases — Fri, 13 Jan 2012 14:01:58 +0100

Carrion Chiropractic Clinic in Tucson announced the launch of a new website, http://www.carrionchiropractic.net. The practice's website was redesigned to enhance patient communications and expand access to pain management information. The practice provides non-surgical pain management for neuro-musculoskeletal disorders of the spine and extremities with a special focus on helping patients heal following car accidents. The new website includes wellness articles, a chiropractor blog, 3D spine simulator and other educational resources for patients. read more (Source: Healthcare IT News Press Releases)

Selective spinal anesthesia for outpatient transurethral prostatectomy (TURP): randomized controlled comparison of chloroprocaine with lidocaine

Acta Anaesthesiologica Scandinavica — Fri, 13 Jan 2012 12:12:15 +0100

ConclusionsSelective spinal anesthesia with chloroprocaine and lidocaine for TURP yielded comparable results for clinical characteristics. Further research on transient neurological symptom and cauda equina risk with chloroprocaine is warranted. (Source: Acta Anaesthesiologica Scandinavica)

An In Vivo Canine Study to Assess Granulomatous Responses in the MedStream Programmable Infusion SystemTM and the SynchroMed II Infusion System®

Pain Medicine — Fri, 13 Jan 2012 05:00:00 +0100

Conclusions. In this in vivo canine model of IT drug delivery, catheter tip granuloma formation was associated with higher concentrations and daily doses of morphine infusion while none were seen with baclofen or saline, and was not associated with catheter type. For both pumps, granulomas were only produced in the presence of morphine infusion. These results suggest that the MedStream Programmable Infusion System has a granuloma safety profile at least equivalent to that of the SynchroMed II pump. (Source: Pain Medicine)

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Spinal interleukin‐6 is an amplifier of arthritic pain

Arthritis and Rheumatism — Fri, 13 Jan 2012 05:00:00 +0100

Conclusions.Not only IL‐6 in the joint is involved in the generation of joint pain but also IL‐6 which is released in the spinal cord. Spinal IL‐6 contributes to central sensitization and thus promotes the widespread hyperalgesia in the course of joint disease. (Source: Arthritis and Rheumatism)

Carrageenan induced phosphorylation of Akt is dependent on neurokinin-1 expressing neurons in the superficial dorsal horn

Molecular Pain — Fri, 13 Jan 2012 05:00:00 +0100

Conclusions: We infer from these data that 1) phosphorylation of Akt in the deep dorsal horn is dependent on prior activation of NK1 receptor bearing cells in lamina I, 2) there are parallel spinal intracellular cascades initiated by the carrageenan injection (Source: Molecular Pain)

[Percutaneous mandibular nerve block using neuro-stimulation guiding through the sigmoid indentation in facial surgery.]

Revue de Stomatologie et de Chirurgie Maxillo-Faciale — Fri, 13 Jan 2012 05:00:00 +0100

DISCUSSION: The complications with this technique, such as failure or arterial puncture, are rare and limited if a nerve stimulator is used. Patient's comfort is improved by intravenous remifentanil sedation in target control infusion mode, associated to prior use of prilocaine and lidocaine cutaneous cream. PMID: 22244733 [PubMed - as supplied by publisher] (Source: Revue de Stomatologie et de Chirurgie Maxillo-Faciale)

Defensive coping styles, anxiety and chronic low back pain

Physiotherapy — Fri, 13 Jan 2012 05:00:00 +0100

Psychological factors, such as anxiety, are associated with differences in pain perception and the prevalence of chronic pain conditions , such as chronic low back pain (CLBP) . Within other clinical populations, anxiety has also been considered in the context of high or low defensiveness to identify distinct coping styles, which have been associated with differences in treatment response and health outcomes . This has rarely been considered within CLBP. (Source: Physiotherapy)

Spinous process-splitting open pedicle screw fusion provides favorable results in patients with low back discomfort and pain compared to conventional open pedicle screw fixation over 1 year after surgery

European Spine Journal — Thu, 12 Jan 2012 06:42:41 +0100

Conclusion In conclusion, SPS open PSF was less damaging to the paraspinal muscle than the conventional open PSF and had a significant clinical effect, reducing low back discomfort over 1 year after the surgery. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00586-011-2146-2Authors Eiji Mori, Department of Orthopaedic Surgery, Spinal Injuries Center, 550-4 Igisu, Iizuka, Fukuoka 820-8508, JapanSeiji Okada, Department of Orthopaedic Surgery, Kyushu University, Graduate School of Medicine, 3-1-1 Maedashi Higashi-ku, Fukuoka, 812-8582 JapanTakayoshi Ueta, Department of Orthopaedic Surgery, Spinal Injuries Center, 550-4 Igisu, Iizuka, Fukuoka 820-8508, JapanYugue Itaru, Department of Orthopaedic Surgery, Spinal Injuries Center, 550-4 Igi...

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Significance of Dynamic Mobility in Restoring Vertebral Body Height in Vertebroplasty [SPINE]

American Journal of Neuroradiology — Thu, 12 Jan 2012 05:00:00 +0100

CONCLUSIONS: The restoration of vertebral body height in vertebroplasty seems to be mostly due to the dynamic mobility of fractured vertebrae; vertebroplasty itself does not contribute much to the restoration of vertebral height. (Source: American Journal of Neuroradiology)

Efficacy of Directional Preference Management for Low Back Pain: A Systematic Review.

Physical Therapy — Thu, 12 Jan 2012 05:00:00 +0100

CONCLUSIONS:/b>Although this systematic review showed mixed results, some evidence was found supporting the effectiveness of DPM when applied to participants with a DP particularly at short and intermediate term follow-up. Further high quality RCTs are warranted to evaluate the effect of DPM applied to people with LBP and a DP. PMID: 22247407 [PubMed - as supplied by publisher] (Source: Physical Therapy)

Peri-sciatic administration of recombinant rat IL-1β induces mechanical allodynia by activation of src-family kinases in spinal microglia in rats.

Experimental Neurology — Thu, 12 Jan 2012 05:00:00 +0100

Authors: Wei XH, Yang T, Wu Q, Xin WJ, Wu JL, Wang YQ, Zang Y, Wang J, Li YY, Liu XG Abstract Previous studies have shown that Interleukin-1 beta (IL-1β) is implicated in the modulation of pain sensitivity. In the present study, we found that a single peri-sciatic administration of rat recombinant IL-1β (rrIL-1β) at doses of 20 and 200pg (100, 1000ng/l, in 200μl volume) induced mechanical allodynia in bilateral hindpaws in rats, lasting for about 50days. No axonal or Schwann cell damage at the drug administration site was found following 1000ng/l rrIL-1β administration. The results of immunofluorescence showed that microglial cells in bilateral spinal dorsal horn were activated after peri-sciatic administration of rrIL-1β (1000ng/l). The immunoreactivity (IR) of Iba1 (a marke...

Competitive Technologies Announces Search for Medical Director to Focus on Calmare(R) Pain Therapy Medical Device

Medical News (via PRIMEZONE) — Wed, 11 Jan 2012 18:03:00 +0100

FAIRFIELD, Conn., Jan. 11, 2012 (GLOBE NEWSWIRE) -- Competitive Technologies, Inc. (OTCQX:CTTC) has initiated a search for a medical director. In late 2011, the Company embarked on a focused marketing program targeting doctors and patients who would benefit from Calmare(r) Scrambler Therapy(tm) treatments. The program has been instrumental in increasing the number of medical practices using the Calmare device to treat patients with chronic neuropathic pain from maladies such as chemotherapy-induced peripheral neuropathy (CIPN), chronic cancer pain, failed back surgery syndrome (FBSS), sciatic and lumbar pain, phantom limb syndrome, post-herpetic neuralgia (PHN), post-surgical neuropathic pain, and brachial plexus neuropathy. Hiring a physician who has experience working with neuropathic pa...

Efficacy of Autologous Platelet-Rich Plasma Use for Orthopaedic Indications: A Meta-Analysis.

The Journal of Bone and Joint Surgery. American volume — Wed, 11 Jan 2012 05:00:00 +0100

CONCLUSIONS: The current literature is complicated by a lack of standardization of study protocols, platelet-separation techniques, and outcome measures. As a result, there is uncertainty about the evidence to support the increasing clinical use of platelet-rich plasma and autologous blood concentrates as a treatment modality for orthopaedic bone and soft-tissue injuries. LEVEL OF EVIDENCE: Therapeutic Level II. Please see Instructions for Authors for a complete description of levels of evidence. PMID: 22241606 [PubMed - as supplied by publisher] (Source: The Journal of Bone and Joint Surgery. American volume)

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Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states

Molecular Pain — Wed, 11 Jan 2012 05:00:00 +0100

Conclusions: Either intranasal or intrathecal pregabalin relieves neuropathic pain behaviours, perhaps due to pregabalin's effect upon anterograde CaValpha2delta-1 protein trafficking from the DRG to the dorsal horn. Intranasal delivery of agents such as pregabalin may be an attractive alternative to systemic therapy for management of neuropathic pain states. (Source: Molecular Pain)

Sprouting of colonic afferent central terminals and increased spinal MAP kinase expression in a mouse model of chronic visceral hypersensitivity

The Journal of Comparative Neurology — Wed, 11 Jan 2012 05:00:00 +0100

AbstractVisceral pain following infection or inflammation is a major clinical problem. Although we have knowledge regarding how peripheral endings of colonic afferents change in disease, their central projections have been overlooked. Using neuroanatomical tracing and colorectal distension (CRD) we aimed to identify colonic afferent central terminals (CACTs), the dorsal horn (DH) neurons activated by colonic stimuli in the thoracolumbar (T10‐L1) DH, and determine how they are altered by post‐inflammatory chronic colonic mechanical hypersensitivity. Retrograde tracing from the colon identified CACTs in the DH, whilst immunohistochemistry for phosphorylated MAP kinase ERK1/2 (pERK) identified DH neurons activated by CRD (80 mmHg). In healthy mice, CACTs were primarily located in DH lamin...

Pick Your Poison

The Poison Review — Wed, 11 Jan 2012 02:35:27 +0100

3 out of 5 stars The Not-so-Nice spice: A Teenage Girl With Palpitations and Dry Mouth. Shah AM et al. Pediatr Emerg Care 2011 Dec;27:1205-7. PubMed Listing This short case report is presented in the form of a diagnostic puzzler. A pregnant 17-year-old woman presents to the emergency department with palpitations, dry mouth, nausea, dizziness, tachycardia (131/min). She reports that several hours before presentation she had ingested a powder from the spice rack at home in an attempt to get high. [Click on the following questions to reveal the answer] What did this patient ingest? expand(document.getElementById('ddet2057913483'));expand(document.getElementById('ddetlink2057913483')) Nutmeg powder. This spice has a reputation as a hallucinogen, but the symptoms associated with ingestion o...

Continuing conservative care versus crossover to radiofrequency kyphoplasty: a comparative effectiveness study on the treatment of vertebral body fractures

European Spine Journal — Tue, 10 Jan 2012 16:59:55 +0100

Conclusion For the vast majority of patients with a VAS ≥5, conservative care did not provide meaningful clinical improvement. In contrast, nearly all patients who underwent radiofrequency kyphoplasty had rapid substantial improvement. Surgery was clearly much more effective than conservative care and should be offered to patients much sooner. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00586-012-2148-8Authors Rahel Bornemann, Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn, Sigmund-Freund-Str. 25, 53105 Bonn, GermanyMichael Hanna, Mercury Medical, 603 W. 115th St., Suite 459, New York, NY 10025, USAKoroush Kabir, Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum ...

360-degree osteosynthesis via a posterolateral transpedicular approach in high-risk patients

European Spine Journal — Tue, 10 Jan 2012 16:59:55 +0100

Conclusion The posterolateral transpedicular approach might be a safe, less-invasive and efficient alternative to anterior–posterior fusion. However, biomechanic efficacy and long-term outcome as compared to the transthoracic technique remains to be studied in a larger patient cohort. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00586-012-2150-1Authors Sven O. Eicker, Department of Neurosurgery, Heinrich-Heine-University, Moorenstraße 5, 40225 Düsseldorf, GermanyJan Frederik Cornelius, Department of Neurosurgery, Heinrich-Heine-University, Moorenstraße 5, 40225 Düsseldorf, GermanyHans-Jakob Steiger, Department of Neurosurgery, Heinrich-Heine-University, Moorenstraße 5, 40225 Düsseldorf, GermanyDaniel Hänggi, Department of Neuro...

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Causes of a painful total knee arthroplasty. Are patients still receiving total knee arthroplasty for extrinsic pathologies?

International Orthopaedics — Tue, 10 Jan 2012 16:59:44 +0100

Conclusions Patients may still be undergoing knee arthroplasty for degenerative lumbar spine and hip osteoarthritis. We suggest heightened awareness at pre- and post-operative assessment and thorough history and examination with the use of diagnostic injections to identify the cause of pain if there is doubt. Content Type Journal ArticleCategory Original PaperPages 1-5DOI 10.1007/s00264-011-1473-6Authors Nawfal Al-Hadithy, Department of Trauma and Orthopaedics, Lister General Hospital, Stevenage, UKHamoun Rozati, Department of Trauma and Orthopaedics, Lister General Hospital, Stevenage, UKMathew D. Sewell, Department of Trauma and Orthopaedics, Lister General Hospital, Stevenage, UKAlex L. Dodds, Department of Trauma and Orthopaedics, Lister General Hospital, Steven...

Are temporomandibular disorder symptoms and diagnoses associated with pubertal development in adolescents? An epidemiological study

Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie — Tue, 10 Jan 2012 16:58:46 +0100

Conclusion Pubertal development increases the probability of self-reported TMD symptoms among girls, while the probability thereof decreases among boys. Independent of sex, pubertal growth increases the prevalence of RDC/TMD-related diagnoses—mainly disk displacement—in both sexes. Content Type Journal ArticleCategory Original articlePages 1-12DOI 10.1007/s00056-011-0056-xAuthors C. Hirsch, Department of Pediatric Dentistry, Dental School, University of Leipzig, Nürnberger Str. 57, 04103 Leipzig, GermanyJ. Hoffmann, Private Practice, Erlau/Crossen, GermanyJ.C. Türp, Dental School, University of Basel, Basel, Switzerland Journal Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopädie Online ISSN 1615-6714Print ISSN 1434-5293 (Source: Journal ...

Management of low back pain with facet joint injections and nerve root blocks under computed tomography guidance. A prospective study

Skeletal Radiology — Tue, 10 Jan 2012 06:41:48 +0100

Conclusions Facet joint and nerve infiltrations under computed tomography guidance constitute an accurate and safe method that could be used to relieve low back pain and minimize the risk of disability. Content Type Journal ArticleCategory Scientific ArticlePages 1-5DOI 10.1007/s00256-011-1353-6Authors Anastasia Fotiadou, Hinchingbrooke Hospital NHS Trust, Huntingdon, PE29 6NT Cambridgeshire, UKAndrew Wojcik, Hinchingbrooke Hospital NHS Trust, Huntingdon, PE29 6NT Cambridgeshire, UKAntony Shaju, Hinchingbrooke Hospital NHS Trust, Huntingdon, PE29 6NT Cambridgeshire, UK Journal Skeletal RadiologyOnline ISSN 1432-2161Print ISSN 0364-2348 (Source: Skeletal Radiology)

Acute Epidural Spinal Hemorrhage from Vasculitis: Resolution with Immunosuppression

Neurocritical Care — Tue, 10 Jan 2012 06:41:25 +0100

Conclusions Immunomodulating therapy should be considered in the management of select patients with spinal vasculitis which may lead to improved clinical outcome and potentially disease resolution. Content Type Journal ArticleCategory Practical PearlPages 1-5DOI 10.1007/s12028-011-9667-8Authors Jeffrey T. Jacob, Department of Neurologic Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USAShota Tanaka, Department of Neurologic Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USAChristopher P. Wood, Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN, USAEelco F. Wijdicks, Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN, USAGiuseppe Lanzino, Department of N...

SRH and HrQoL: does social position impact differently on their link with health status?

BMC Public Health - Latest articles — Tue, 10 Jan 2012 05:00:00 +0100

Conclusions: Both SRH and HRQoL were lower among those reporting functional limitations or chronic low back pain. However, the change varied according SEP and the measure. In relative term, the negative impact of a given health condition seems to be greater on SRH and lower on HRQoL for people with higher SEP in comparison with people with low SEP. Using SRH could thus decrease socioeconomic differences. In contrast using HRQoL could increase these differences, suggesting being cautious when using these indicators for analyzing health disparities. (Source: BMC Public Health - Latest articles)

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Heavy burden of non-communicable diseases at early age and gender disparities in an adult population of Burkina Faso: World Health Survey

BMC Public Health - Latest articles — Tue, 10 Jan 2012 05:00:00 +0100

Conclusions: Our work suggests that social inequality extends into the distribution of non-communicable diseases among social groups and supports the thesis of a differential vulnerability in Burkinabe women. It raises the possibility of an abnormally high rate of premature morbidity that could manifest as a form of premature aging in the adult population. Increased prevention, screening and treatment are needed in Burkina Faso to address high prevalence and gender inequalities in non-communicable diseases. (Source: BMC Public Health - Latest articles)

In This Issue [This Week in PNAS]

Proceedings of the National Academy of Sciences — Tue, 10 Jan 2012 05:00:00 +0100

Unconventional muscle pain signalingpnas;109/2/347/UNFIG01F1unfig01Substance P can be inhibited by a known isoflavone isolated from soybeans. Image courtesy of Chia-Wen Wong (Institute of Zoology, National Taiwan University) and Wei-Li Wu (Institute of Biomedical Sciences, Academia Sinica).Substance P (SP) is a pain neurotransmitter that helps excite and transmit pain signals from neural cells in many organs. Though high levels of SP in muscle tissues and spinal fluid are frequently associated with chronic muscle pain, the role of SP in muscle pain transmission and perception remains unclear. Chia-Ching John Lin et al. (pp. 363–364) used mice that lacked SP signaling to test how... (Source: Proceedings of the National Academy of Sciences)

Nemo syndrome (incontinentia pigmenti) and systemic lupus erythematosus: a new disease association.

Lupus — Tue, 10 Jan 2012 05:00:00 +0100

This report may suggest a role for NF-kB essential modulator in the pathogenesis of SLE, in the context of thecomplex immunologic deficiencies increasingly associated with autoimmune diseases. PMID: 22235006 [PubMed - as supplied by publisher] (Source: Lupus)

Young woman with lasting back pain.

Tidsskrift for den Norske Laegeforening — Tue, 10 Jan 2012 05:00:00 +0100

Young woman with lasting back pain. Tidsskr Nor Laegeforen. 2012 Jan 10;132(1):48 Authors: Tonde AK, Berild D PMID: 22240829 [PubMed - as supplied by publisher] (Source: Tidsskrift for den Norske Laegeforening)